- Search results for Cay10010468-%25
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5 products were found matching "Cay10010468-%25"!
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Item number: Cay10010486-25
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator...
Keywords: | 14,15-Epoxyeicosa-8(Z)-enoic Acid, 13[(2R,3S)-3-pentyloxiranyl]-8Z-tridecenoic acid |
Application: | Vasodilator agonist |
CAS | 519038-93-8 |
MW: | 324.5 D |
From 65.00€
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Item number: Cay10010469-25
ADHP is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H2O2. This colorless, non-fluorescent reagent reacts with H2O2 to produce the fluorescent compound resorufin, which can be analyzed using an excitation wavelength of 520-550 nm and an emission wavelength...
Keywords: | A 6550, ADHP, Amplex Red(R), 1-(3,7-dihydroxy-10H-phenoxazin-10-yl)-ethanone |
Application: | HRP substrate |
CAS | 119171-73-2 |
MW: | 257.2 D |
From 34.00€
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Item number: Cay10010466-25
SP6000125 is a pan-inhibitor of JNK (IC50s = 0.04, 0.04, and 0.09 µM for JNK1, -2, and -3, respectively). It is greater than 300-fold selective for these enzymes over a panel of 17 additional kinases at 10 µM. SP6000125 reduces LPS-induced production of IL-1beta, IL-8, and TNF-alpha in isolated human peripheral...
Keywords: | 1PMV, NSC 75890, Pyrazolanthrone, anthra[1,9-cd]pyrazol-6(2H)-one |
Application: | JNK inhibitor |
CAS | 129-56-6 |
MW: | 220.2 D |
From 60.00€
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Item number: Cay10010568-25
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors such as epidermal growth factor (EGF) or platelet-derived growth factor (PDGF)...
Keywords: | NSC 651712, 3-amino-4-(1H-indol-5-ylmethylene)-2-pentenetricarbonitrile |
Application: | PDGF receptor kinase inhibitor |
CAS | 134036-53-6 |
MW: | 259.3 D |
From 77.00€
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Item number: Cay10010368-25
Raf-1 is a proto-oncogene serine/threonine protein kinase that signals from Ras to the MAPK/ERK signaling pathway. This pathway mediates basic cellular functions, including proliferation, differentiation, and survival. GW 5074 is a potent, selective, and cell-permeable inhibitor of Raf-1 (IC50 = 9 nM). It blocks...
Keywords: | 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one |
Application: | Raf-1 inhbitor |
CAS | 220904-83-6 |
MW: | 520.9 D |
From 50.00€
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