- Search results for Cay10010463
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12 products were found matching "Cay10010463"!
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Item number: Cay10010469-10
ADHP is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H2O2. This colorless, non-fluorescent reagent reacts with H2O2 to produce the fluorescent compound resorufin, which can be analyzed using an excitation wavelength of 520-550 nm and an emission wavelength...
Keywords: | A 6550, ADHP, Amplex Red(R), 1-(3,7-dihydroxy-10H-phenoxazin-10-yl)-ethanone |
Application: | HRP substrate |
CAS | 119171-73-2 |
MW: | 257.2 D |
From 34.00€
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Item number: Cay10010466-10
SP6000125 is a pan-inhibitor of JNK (IC50s = 0.04, 0.04, and 0.09 µM for JNK1, -2, and -3, respectively). It is greater than 300-fold selective for these enzymes over a panel of 17 additional kinases at 10 µM. SP6000125 reduces LPS-induced production of IL-1beta, IL-8, and TNF-alpha in isolated human peripheral...
Keywords: | 1PMV, NSC 75890, Pyrazolanthrone, anthra[1,9-cd]pyrazol-6(2H)-one |
Application: | JNK inhibitor |
CAS | 129-56-6 |
MW: | 220.2 D |
From 60.00€
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Item number: Cay10010468-5
15-Lipoxygenase inhibitor 1 is a 15-lipoxygenase (15-LO) inhibitor (IC50 = 18 µM). It scavenges DPPH (Cay-14805) radicals in a cell-free assay (IC50 = 69.6 µM).Formal Name: 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine. CAS Number: 928853-86-5. Synonyms: 15-LO Inhibitor 1, 4-MMPB. Molecular Formula:...
Keywords: | 15-LO Inhibitor 1, 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine |
Application: | 15-LO inhibitor |
CAS | 928853-86-5 |
MW: | 313.4 D |
From 43.00€
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Item number: Cay10460-10
The stress-activated p38 mitogen-activated protein kinase (MAPK) plays a critical role in regulating the production of proinflammatory cytokines such as tumor necrosis factor and interleukin-1. Doramapimod is a highly potent inhibitor of p38 MAPK with a Kd value of 0.1 nM that blocks TNFalpha release in...
Keywords: | BIRB-796, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]-urea |
Application: | p38 MAPK inhibitor |
CAS | 285983-48-4 |
MW: | 527.7 D |
From 35.00€
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Item number: Cay10010364-100
Fatty acid binding protein 5 (FABP5) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids. Members of this protein family exhibit high affinity for lipophilic ligands and were named according to the tissue from which they were initially isolated. FABP5 is found in skin,...
Keywords: | PA-FABP, PA-FABP, E-FABP {ECO:0000303|PubMed:8092987}, E-FABP {ECO:0000303|PubMed:8092987}, Fatty acid-binding protein,... |
Application: | WB |
MW: | 18 kD |
530.00€
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Item number: Cay10010263-1
Formulation: (Request formulation change), 10 ml of 250 mM Tris-HCl, pH 7.6, containing 750 mM sodium chloride, 5% NP-40, 2.5% sodium deoxycholate, and 0.5% SDS.
Application: | Kit component |
50.00€
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Item number: Cay10013-500
Prostaglandin A1 (PGA1) is one of the cyclopentenone prostaglandins, which have well documented antimitotic and antiproliferative effects. The activity of the compounds in this class, which includes prostaglandins in both the A- and J-series, may result from changes in gene expression and the interaction with...
Keywords: | PGA1-biotin, N-9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oyl-N'-biotinoyl-1,6-diaminopentane |
Application: | Affinity probe |
MW: | 646.9 D |
From 44.00€
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Item number: Cay10010-50
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: | PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 14152-28-4 |
MW: | 336.5 D |
From 48.00€
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Item number: Cay10010426-5
KRP 203 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist. It selectively induces calcium mobilization in CHO-K1 cells expressing mouse S1P1 over mouse S1P3 and S1P4 (EC50s = 0.84, >1,000, and 9.61 nM, respectively). In vivo, KRP 203 (0.3 mg/kg) prevents the development of wasting syndrome, decreases diarrhea...
Keywords: | Mocravimod (hydrochloride), 2-amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol,... |
Application: | S1P1 receptor agonist |
CAS | 509088-69-1 |
MW: | 480.4 D |
From 68.00€
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Item number: Cay10010246-5
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...
Keywords: | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
Application: | GSK inhibitor |
CAS | 280744-09-4 |
MW: | 371.2 D |
From 98.00€
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Item number: Cay10010146-1
Soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold enzyme family that catalyzes the hydrolysis of bioactive fatty acid epoxides to inactive vicinal diols. It is a homodimer in which each subunit is composed of two domains, a C-terminal epoxide hydrolase domain and an N-terminal phosphatase...
Keywords: | Anti-CEH, Anti-CEH, Anti-Epoxide hydratase, Anti-Epoxide hydratase, Anti-Lipid-phosphate phosphatase, Anti-Lipid-phosphate... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, murine, rat |
422.00€
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Item number: Cay10010406-5
Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug. Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice...
Keywords: | N-methyl-9alpha,11alpha,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-amide |
Application: | Bioactive lipid assays |
MW: | 471.5 D |
From 94.00€
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