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Item number: Cay10010422-10

Nilotinib is an inhibitor of wild-type and mutant Bcr-Abl (IC50s = 15 and 9-400 nM, respectively). It is selective for wild-type and mutant Bcr-Abl over Src and LYN (IC50s = >5,000 nM for both). Nilotinib inhibits Bcr-Abl autophosphorylation and cell proliferation in Ba/F3 cells expressing wild-type or mutant...

Keywords:	AMN107,...
Application:	Bcr inhibitor, Abl inhibitor
CAS	641571-10-0
MW:	529.5 D

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