- Search results for Cay10010401
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8 products were found matching "Cay10010401"!
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Item number: Cay10010401-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Keywords: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
Application: | SIRT1 inhibitor/activator screening |
Species reactivity: | human |
467.00€
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Item number: Cay10010406-1
Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug. Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice...
Keywords: | N-methyl-9alpha,11alpha,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-amide |
Application: | Bioactive lipid assays |
MW: | 471.5 D |
From 94.00€
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Item number: Cay10010405-1
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2alpha ethyl amide (17-phenyl trinor PGF2alpha ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2alpha ethyl amide....
Keywords: | 15-keto-Bimatoprost, 17-phenyl trinor PGF2alpha ethyl amide,... |
Application: | F-series PG analog |
CAS | 1163135-96-3 |
MW: | 413.5 D |
From 92.00€
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Item number: Cay10010404-1
N-Acetyl-DL-penicillamine is a chelating agent. It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM. N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the...
Keywords: | NAPA, NSC 28039, NSC 92752, N-acetyl-3-mercapto-valine |
Application: | Chelator |
CAS | 59-53-0 |
MW: | 191.2 D |
From 100.00€
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Item number: Cay10010240-1
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Olomoucine is a cdk inhibitor that acts by competing for the ATP binding site of the kinase. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), Cdk2/cyclin A (IC50...
Keywords: | 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-ethanol |
Application: | CDK inhibitor |
CAS | 101622-51-9 |
MW: | 298.3 D |
From 43.00€
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Item number: Cay10010470-1
AL 8810 is an 11beta-fluoro analog of prostaglandin F2alpha (PGF2alpha) which acts as a potent and selective antagonist at the FP receptor. AL 8810 ethyl amide is an analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide. This modification is analogous to the PG N-ethyl amides, as...
Keywords: | 9alpha,15R-dihydroxy-11beta-fluoro-15-92,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dion-1-oic acid,... |
Application: | FP receptor antagonist |
MW: | 429.6 D |
From 119.00€
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Item number: Cay10010740-1
Cellular prion protein (PrPc) is a cell surface glycoprotein expressed in brain, spinal cord, and several peripheral tissues that if mutated to the protease-resistant isoform PrPSc (scrapie PrP, PrPres) can result in one of several fatal neurodegenerative diseases. Prion diseases, including mad cow disease (bovine...
Keywords: | 3-(4-Nitrophenyl)-1-phenyl-2-pyrazolin-5-one, 2,4-dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one |
Application: | PrPc accumulation inhibitor |
CAS | 34320-83-7 |
MW: | 281.3 D |
From 38.00€
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Item number: Cay10010410-1
Four G protein-coupled receptors, EP1-4, initiate cellular signaling in response to prostaglandin PGE2. The receptor EP1 acts via Galphaq to evoke diverse effects, including renal vasoconstriction, bronchoconstriction, hyperalgesia, allodynia, gastric protection, hyperthermia, and sleep inhibition. GW 848687X is a...
Keywords: | 6-[2-[5-chloro-2-[(2,4-digluorophenyl)methoxy]phenyl]-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid |
Application: | EP1 receptor antagonist |
CAS | 612831-24-0 |
MW: | 441.9 D |
From 119.00€
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