- Search results for Cay10010382-%25
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8 products were found matching "Cay10010382-%25"!
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Item number: Cay10010383-25
The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates...
Keywords: | 1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt |
Application: | Bioactive lipid assays |
MW: | 1908.2 D |
From 115.00€
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Item number: Cay10010380-25
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2alpha (ent-8-iso-15(S)-PGF2alpha) is a potent...
Keywords: | ent-15-epi-F2t-Isoprostane, ent-8-iso-15-epi-PGF2alpha, 9beta,11beta,15S-trihydroxy-(12beta)-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 214748-66-0 |
MW: | 354.5 D |
From 161.00€
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Item number: Cay10010388-25
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2-fluorescein is a fluorescent probe for any protein with a high-affinity binding interaction with...
Keywords: | 1-(1-octadecanoyl-fluorescein-2R-octadecanoylphosphatidyl)inositol-4,5-bisphosphate, pentatriethylammonium salt |
Application: | Bioactive lipid assays |
MW: | 1625.8 D |
From 115.00€
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Item number: Cay10010368-25
Raf-1 is a proto-oncogene serine/threonine protein kinase that signals from Ras to the MAPK/ERK signaling pathway. This pathway mediates basic cellular functions, including proliferation, differentiation, and survival. GW 5074 is a potent, selective, and cell-permeable inhibitor of Raf-1 (IC50 = 9 nM). It blocks...
Keywords: | 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one |
Application: | Raf-1 inhbitor |
CAS | 220904-83-6 |
MW: | 520.9 D |
From 50.00€
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Item number: Cay10010398-25
CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors. In rats, oral CB-13 (3 mg/kg) potently blocks CB1-dependent neuropathic mechanical hyperalgesia, shows limited brain penetration, and exhibits good oral bioavailability. CB-13 does not possess genotoxic potential, as indicated by...
Keywords: | CRA-13, 1-naphthalenyl[4-(pentylox)-1-naphthalenyl]-methanone |
Application: | Dual CB1 / CB2 receptor agonist |
CAS | 432047-72-8 |
MW: | 368.5 D |
From 74.00€
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Item number: Cay10010312-25
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
Keywords: | NSC 676484, RG-50875, Tyrphostin 25, Tyrphostin AG-82, 2-[(3,4,5-trihydroxyphenyl)methylene]-propanedinitrile |
Application: | EGF receptor kinase inhibitor |
CAS | 118409-58-8 |
MW: | 202.2 D |
From 38.00€
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Item number: Cay10010372-25
GW 842166X is a cannabinoid 2 (CB2) receptor agonist. It increases intracellular calcium mobilization induced by the CB receptor agonist CP 55,940 (Cay-13241) in HEK cells co-expressing a chimeric Galphaq/05 protein and the human CB2 receptor (EC50 = 7.78 µM). GW 842166X is selective for CB2 over the CB1 receptor...
Keywords: | 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)-5-pyrimidinecarboxamide |
Application: | CB2 receptor agonist |
CAS | 666260-75-9 |
MW: | 449.3 D |
From 30.00€
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Item number: Cay10010638-25
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has...
Keywords: | (±)18-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 133268-58-3 |
MW: | 320.5 D |
From 196.00€
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