- Search results for Cay10010374
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15 products were found matching "Cay10010374"!
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Item number: Cay10010743-10
Capsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It induces inward currents in HEK293 cells expressing rat transient receptor potential vanilloid 1 (TRPV1, EC50 = 0.64 µM at neutral pH), an effect that can be blocked by the TRPV1 inhibitor A-425619. Capsaicin (10...
Keywords: | N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide |
Application: | Metabolic studies |
CAS | 404-86-4 |
MW: | 305.4 D |
From 43.00€
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Item number: Cay10010372-5
GW 842166X is a cannabinoid 2 (CB2) receptor agonist. It increases intracellular calcium mobilization induced by the CB receptor agonist CP 55,940 (Cay-13241) in HEK cells co-expressing a chimeric Galphaq/05 protein and the human CB2 receptor (EC50 = 7.78 µM). GW 842166X is selective for CB2 over the CB1 receptor...
Keywords: | 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)-5-pyrimidinecarboxamide |
Application: | CB2 receptor agonist |
CAS | 666260-75-9 |
MW: | 449.3 D |
From 30.00€
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Item number: Cay10010375-1
5-Iodotubercidin is an inhibitor of adenosine kinase (IC50 = 0.026 µM). It inhibits protein kinase A (PKA), phosphorylase kinase, casein kinase 1 (CK1), CK2, and PKC (IC50s = 5-10, 5-10, 0.4, 10.9, and 0.4 µM, respectively). 5-Iodotubercidin is also an inhibitor of severe acute respiratory syndrome coronavirus 2...
Keywords: | Itu, NSC 113939, 5-iodo-7-beta-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Application: | MAPK Inhibitor |
CAS | 24386-93-4 |
MW: | 392.2 D |
From 76.00€
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Item number: Cay10010344-5
Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-kappaB activation (IC50 = ~13 µM) and potentiates apoptosis in human myeloid...
Keywords: | MK-733,... |
Application: | HMG-CoA reductase inhibitor |
CAS | 79902-63-9 |
MW: | 418.6 D |
From 43.00€
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Item number: Cay10010334-10
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid |
Application: | HMG-CoA reductase inhibitor |
CAS | 93957-54-1 |
MW: | 411.5 D |
From 54.00€
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Item number: Cay10010364-100
Fatty acid binding protein 5 (FABP5) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids. Members of this protein family exhibit high affinity for lipophilic ligands and were named according to the tissue from which they were initially isolated. FABP5 is found in skin,...
Keywords: | PA-FABP, PA-FABP, E-FABP {ECO:0000303|PubMed:8092987}, E-FABP {ECO:0000303|PubMed:8092987}, Fatty acid-binding protein,... |
Application: | WB |
MW: | 18 kD |
530.00€
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Item number: Cay10010314-10
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
Keywords: | Tyrphostin 47, Tyrphostin AG-213, 2-cyano-3-(3,4-dihydroxyphenyl)-2E-propenethioamide |
Application: | EGF receptor kinase inhibitor |
CAS | 122520-86-9 |
MW: | 220.2 D |
From 77.00€
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Item number: Cay10010324-250
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a central regulator of adipocyte differentiation and is the principle target of the thiazolidinedione (TZD) class of antidiabetic drugs. Harmine is a beta-carboline alkaloid that was first isolated from seeds of Peganum harmala (Syrian rue) and...
Keywords: | 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole |
Application: | MS, beta-carboline alkaloid |
CAS | 442-51-3 |
MW: | 212.3 D |
From 43.00€
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Item number: Cay10070-100
15-epi Prostaglandin A1 (15-epi PGA1) is the 15(R) stereoisomer of PGA1. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive...
Keywords: | 15-epi PGA1, 9-oxo-15R-hydroxy-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 20897-92-1 |
MW: | 336.5 D |
From 43.00€
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Item number: Cay10010974-1
Xanthine Oxidase Standard has been tested and formulated to work exclusively with Cayman's Xanthine Oxidase Fluorometric Assay Kit (Cay-10010895). Please visit Xanthine Oxidase Fluorometric Assay Kit (Cay-10010895) for the kit protocol, procedures, and product handling.Formulation: 50 mU of xanthine oxidase. Origin:...
Application: | Kit component |
20.00€
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