- Search results for Cay10010333-%25
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6 products were found matching "Cay10010333-%25"!
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Item number: Cay10010337-25
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt, hydrate |
Application: | Hydroxymethylglutaryl-coenzyme A reductase inhibitor |
MW: | 410.5 D |
From 35.00€
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Item number: Cay10010334-25
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid |
Application: | HMG-CoA reductase inhibitor |
CAS | 93957-54-1 |
MW: | 411.5 D |
From 54.00€
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Item number: Cay10010339-25
Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin (Cay-10010338).Formal Name:...
Keywords: | 2-methyl-1S,2,3R,7S,8S,8aR-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthal... |
Application: | NF-kappaB activation inhibitor |
CAS | 75225-50-2 |
MW: | 444.5 D |
From 50.00€
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Item number: Cay10010343-25
Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the "statin" class of cholesterol-lowering drugs. Pravastatin is a HMG-CoA reductase inhibitor that is a ring hydroxylated metabolite of mevastatin. It is a competitive inhibitor...
Keywords: | 1S,2S,6S,7S,8R,8aR-hexahydro-betaR,deltaR,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid,... |
Application: | Potent HMG-CoA reductase inhibitor |
CAS | 81131-70-6 |
MW: | 446.5 D |
From 35.00€
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Item number: Cay10010313-25
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
Keywords: | Tyrphostin 46, Tyrphostin AG-99, 2-cyano-3-(3,4-dihydroxyphenyl)-2E-propenamide |
Application: | EGF receptor kinase inhibitor |
CAS | 122520-85-8 |
MW: | 204.2 D |
From 46.00€
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Item number: Cay10010383-25
The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates...
Keywords: | 1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt |
Application: | Bioactive lipid assays |
MW: | 1908.2 D |
From 115.00€
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