- Search results for Cay10010329-%25
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7 products were found matching "Cay10010329-%25"!
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Item number: Cay10010399-25
SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a range of other kinases, including other MAP kinases (ERKs,...
Keywords: | 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol |
Application: | MAP kinases Inhibitor |
CAS | 152121-30-7 |
MW: | 331.3 D |
From 39.00€
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Item number: Cay10010339-25
Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin (Cay-10010338).Formal Name:...
Keywords: | 2-methyl-1S,2,3R,7S,8S,8aR-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthal... |
Application: | NF-kappaB activation inhibitor |
CAS | 75225-50-2 |
MW: | 444.5 D |
From 50.00€
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Item number: Cay10010390-25
Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA, Cay-90310). DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to protectin D1 enzymatically. Protectin D1 increases phagocytosis of apoptotic polymorphonuclear leukocytes (PMNs) by macrophages in a...
Keywords: | Neuroprotectin D1, Neuroprotectin D1/Protectin D1, NPD1, PD1, 10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid |
Application: | Specialized pro-resolving mediator (SPM) |
CAS | 660430-03-5 |
MW: | 360.5 D |
From 163.00€
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Item number: Cay10010396-25
TPalpha and TPbeta are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). Although their distinct physiological functions have not been fully elucidated, TPbeta is believed to be responsible for vascular endothelial growth factor-induced...
Keywords: | N-(tert-butylcarbamoyl)-2-(3-methoxyphenoxy)-5-nitrobenzenesulfonamide |
Application: | TP receptor antagonist |
CAS | 945716-28-9 |
MW: | 423.4 D |
From 48.00€
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Item number: Cay10010398-25
CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors. In rats, oral CB-13 (3 mg/kg) potently blocks CB1-dependent neuropathic mechanical hyperalgesia, shows limited brain penetration, and exhibits good oral bioavailability. CB-13 does not possess genotoxic potential, as indicated by...
Keywords: | CRA-13, 1-naphthalenyl[4-(pentylox)-1-naphthalenyl]-methanone |
Application: | Dual CB1 / CB2 receptor agonist |
CAS | 432047-72-8 |
MW: | 368.5 D |
From 74.00€
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Item number: Cay10010239-25
The development of selective, cell-permeable protein kinase inhibitors for the treatment of cancer, inflammation, and other diseases, is a major focus of drug development efforts. Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta...
Keywords: | 9-Bromopaullone, NSC 664704, 9-bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one |
Application: | CDK inhibitor, GSK-3 beta inhibitor |
CAS | 142273-20-9 |
MW: | 327.2 D |
From 66.00€
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Item number: Cay10010093-25
1-Oleoyl-2-hydroxy-sn-glycero-3-PA (1-Oleoyl LPA) is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by...
Keywords: | 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid |
Application: | Bioactive lipid assays |
CAS | 65528-98-5 |
MW: | 436.5 D |
From 35.00€
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