6 products were found matching "Cay10010309-%25"!

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Protectin D1
Protectin D1

Item number: Cay10010390-25

Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA, Cay-90310). DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to protectin D1 enzymatically. Protectin D1 increases phagocytosis of apoptotic polymorphonuclear leukocytes (PMNs) by macrophages in a...
Keywords: Neuroprotectin D1, Neuroprotectin D1/Protectin D1, NPD1, PD1, 10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid
Application: Specialized pro-resolving mediator (SPM)
CAS 660430-03-5
MW: 360.5 D
From 163.00€ *
Review
CAY10554
CAY10554

Item number: Cay10010301-25

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and...
Keywords: BML-259, N-[5-(1-methylethyl)2-thiazolyl]-benzeneacetamide
Application: CDK5 inhibitor, CDK2 inhibitor
CAS 267654-00-2
MW: 260.4 D
From 86.00€ *
Review
AG-18
AG-18

Item number: Cay10010300-25

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF)...
Keywords: RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin AG-18, 2-[(3,4-dihydroxyphenyl)methylene]-propanedinitrile
Application: EGF receptor kinase inhibitor
CAS 118409-57-7
MW: 186.1 D
From 46.00€ *
Review
SB 202190
SB 202190

Item number: Cay10010399-25

SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a range of other kinases, including other MAP kinases (ERKs,...
Keywords: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol
Application: MAP kinases Inhibitor
CAS 152121-30-7
MW: 331.3 D
From 39.00€ *
Review
Lovastatin Hydroxy Acid (sodium salt)
Lovastatin Hydroxy Acid (sodium salt)

Item number: Cay10010339-25

Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin (Cay-10010338).Formal Name:...
Keywords: 2-methyl-1S,2,3R,7S,8S,8aR-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthal...
Application: NF-kappaB activation inhibitor
CAS 75225-50-2
MW: 444.5 D
From 50.00€ *
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1-Oleoyl-2-hydroxy-sn-glycero-3-PA
1-Oleoyl-2-hydroxy-sn-glycero-3-PA

Item number: Cay10010093-25

1-Oleoyl-2-hydroxy-sn-glycero-3-PA (1-Oleoyl LPA) is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by...
Keywords: 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid
Application: Bioactive lipid assays
CAS 65528-98-5
MW: 436.5 D
From 35.00€ *
Review