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Item number: Cay10010267-25

SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 3-12 µM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. In synovial fibroblasts stimulated with interleukin (IL)-1beta, SC-514 attenuates NF-kappaB-mediated expression of IL-6,...

Keywords:	4-amino-[2,3'-bithiophene]-5-carboxamide
Application:	IKK2 inhibitor
CAS	354812-17-2
MW:	224.3 D

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