- Search results for Cay10010265-%25
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2 products were found matching "Cay10010265-%25"!
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Item number: Cay10010266-25
The transcription factor NF-kappaB plays a key role in regulating over 150 target genes including the expression of inflammatory cytokines, chemokines, immunoreceptors, and cell adhesion molecules. In the cytoplasm, inactive NF-kappaB complexes are bound to an inhibitor IkappaB. However in response to certain...
Keywords: | 3-[(4-methylphenyl)sulfonyl]-(2E)-propenenitrile |
Application: | NF-kappaB activation inhibitor |
CAS | 19542-67-7 |
MW: | 207.3 D |
From 66.00€
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Item number: Cay10010267-25
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 3-12 µM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. In synovial fibroblasts stimulated with interleukin (IL)-1beta, SC-514 attenuates NF-kappaB-mediated expression of IL-6,...
Keywords: | 4-amino-[2,3'-bithiophene]-5-carboxamide |
Application: | IKK2 inhibitor |
CAS | 354812-17-2 |
MW: | 224.3 D |
From 60.00€
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