10 products were found matching "Cay10010245"!
No results were found for the filter!
AG-1478
Item number: Cay10010244-5
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTK. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor receptor (EGFR) kinase and block...
| Keywords: | NSC 693255, Tyrphostin AG-1478, N-(3-chlorophenyl)-6,7-dimethoxy-4-quinazolinamine |
| Application: | EGF receptor kinase inhibitor |
| CAS | 153436-53-4 |
| MW: | 315.8 D |
From 30.00€
*
LY223982
Item number: Cay10010024-5
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from the 5-lipoxygenase pathway of arachidonic acid metabolism and is an important mediator of the inflammatory process. The benzophenone dicarboxylic acid derivative LY223982 is a potent BLT1 receptor antagonist. It inhibits the specific binding of...
| Keywords: | CGS 23131, SKF 107324, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexenyl]oxy]-benzenepropanoic acid |
| Application: | BLT1 receptor antagonist |
| CAS | 117423-74-2 |
| MW: | 502.6 D |
From 38.00€
*
SB-216763
Item number: Cay10010246-5
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...
| Keywords: | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Application: | GSK inhibitor |
| CAS | 280744-09-4 |
| MW: | 371.2 D |
From 98.00€
*
H-8 (hydrochloride)
Item number: Cay10010249-5
The H series isoquinolinesulfonamide protein kinase (PK) inhibitors are widely used to block signaling pathways to elucidate mechanisms of cellular regulation and signal transduction. H-8, an isoquinolinesulfonamide protein kinase (PK) inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for...
| Keywords: | Protein Kinase Inhibitor H-8, N-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide, dihydrochloride |
| Application: | PKA inhibitor, PKG inhibitor |
| CAS | 113276-94-1 |
| MW: | 338.3 D |
From 50.00€
*
AG-825
Item number: Cay10010243-5
The HER2/Neu proto-oncogene is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases (RTK) which includes EGFR, HER2/Neu, HER3 and HER4. Overexpression of HER2/Neu occurs in 25-30% of human breast and ovarian cancer. AG-825 is a selective ATP-competitive inhibitor of the...
| Keywords: | Tyrphostin AG-825, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide |
| Application: | HER-2/neu inhibitor |
| CAS | 149092-50-2 |
| MW: | 397.5 D |
From 38.00€
*
Olomoucine
Item number: Cay10010240-5
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Olomoucine is a cdk inhibitor that acts by competing for the ATP binding site of the kinase. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), Cdk2/cyclin A (IC50...
| Keywords: | 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-ethanol |
| Application: | CDK inhibitor |
| CAS | 101622-51-9 |
| MW: | 298.3 D |
From 43.00€
*
AG-17
Item number: Cay10010248-5
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of protein tyrosine kinases. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth...
| Keywords: | GCP 5126, Malonoben, NSC 242557, RG-50872, SF 6847, Tyrphostin 9, Tyrphostin AG-17,... |
| Application: | EGF receptor kinase inhibitor |
| CAS | 10537-47-0 |
| MW: | 282.4 D |
From 38.00€
*
AG-494
Item number: Cay10010242-5
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative, compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
| Keywords: | Tyrphostin AG-494, 2E-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide |
| Application: | EGF receptor kinase inhibitor |
| CAS | 133550-35-3 |
| MW: | 280.3 D |
From 46.00€
*
SB-415286
Item number: Cay10010247-5
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli such as insulin, growth factors, cell specification factors, and cell adhesion. Its activity regulates many cell functions including the control of cell division, apoptosis, and...
| Keywords: | 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione |
| Application: | GSK inhibitor |
| CAS | 264218-23-7 |
| MW: | 359.7 D |
From 43.00€
*
Pentosidine (trifluoroacetate salt)
Item number: Cay10010254-5
Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell...
| Keywords: | alphaS-amino-2-[[4S-amino-4-carboxybutyl]amino]-4H-imidazo[4,5-b]pyridine-4-hexanoic acid |
| Application: | Biomarker for AGEs |
| CAS | 225784-09-8 |
| MW: | 378.4 D |
From 323.00€
*