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Item number: Cay10010241-250

AICAR is an activator of AMP-activated protein kinase (AMPK). It increases AMPK kinase activity in isolated hepatocytes (EC50 = ~500 µM) and reduces HMG-CoA reductase activity and fatty acid and sterol synthesis in these cells. AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of control cells and...

Keywords:	Acadesine, AICA-Riboside, NSC 105823, 5-amino-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide
Application:	AMPK activator
CAS	2627-69-2
MW:	258.2 D

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