- Search results for Cay10010241
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8 products were found matching "Cay10010241"!
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Item number: Cay10010241-50
AICAR is an activator of AMP-activated protein kinase (AMPK). It increases AMPK kinase activity in isolated hepatocytes (EC50 = ~500 µM) and reduces HMG-CoA reductase activity and fatty acid and sterol synthesis in these cells. AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of control cells and...
Keywords: | Acadesine, AICA-Riboside, NSC 105823, 5-amino-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide |
Application: | AMPK activator |
CAS | 2627-69-2 |
MW: | 258.2 D |
From 64.00€
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Item number: Cay10010244-1
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTK. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor receptor (EGFR) kinase and block...
Keywords: | NSC 693255, Tyrphostin AG-1478, N-(3-chlorophenyl)-6,7-dimethoxy-4-quinazolinamine |
Application: | EGF receptor kinase inhibitor |
CAS | 153436-53-4 |
MW: | 315.8 D |
From 30.00€
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Item number: Cay10010024-1
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from the 5-lipoxygenase pathway of arachidonic acid metabolism and is an important mediator of the inflammatory process. The benzophenone dicarboxylic acid derivative LY223982 is a potent BLT1 receptor antagonist. It inhibits the specific binding of...
Keywords: | CGS 23131, SKF 107324, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexenyl]oxy]-benzenepropanoic acid |
Application: | BLT1 receptor antagonist |
CAS | 117423-74-2 |
MW: | 502.6 D |
From 38.00€
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Item number: Cay10010240-1
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Olomoucine is a cdk inhibitor that acts by competing for the ATP binding site of the kinase. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), Cdk2/cyclin A (IC50...
Keywords: | 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-ethanol |
Application: | CDK inhibitor |
CAS | 101622-51-9 |
MW: | 298.3 D |
From 43.00€
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Item number: Cay10010247-1
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli such as insulin, growth factors, cell specification factors, and cell adhesion. Its activity regulates many cell functions including the control of cell division, apoptosis, and...
Keywords: | 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione |
Application: | GSK inhibitor |
CAS | 264218-23-7 |
MW: | 359.7 D |
From 43.00€
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Item number: Cay10010243-1
The HER2/Neu proto-oncogene is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases (RTK) which includes EGFR, HER2/Neu, HER3 and HER4. Overexpression of HER2/Neu occurs in 25-30% of human breast and ovarian cancer. AG-825 is a selective ATP-competitive inhibitor of the...
Keywords: | Tyrphostin AG-825, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide |
Application: | HER-2/neu inhibitor |
CAS | 149092-50-2 |
MW: | 397.5 D |
From 38.00€
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Item number: Cay10010254-1
Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell...
Keywords: | alphaS-amino-2-[[4S-amino-4-carboxybutyl]amino]-4H-imidazo[4,5-b]pyridine-4-hexanoic acid |
Application: | Biomarker for AGEs |
CAS | 225784-09-8 |
MW: | 378.4 D |
From 323.00€
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Item number: Cay10010624-1
Oleic acid is a monounsaturated fatty acid and is one of the major components of membrane phospholipids. Oleic acid contributes about 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets. Oleic acid-biotin was designed to allow oleic acid to be detected in...
Keywords: | 9Z-octadecnoyl-N'-biotinoyl-1,5-diaminopentane |
Application: | Bioactive lipid assays |
MW: | 522.8 D |
From 77.00€
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