18 products were found matching "Cay10010200"!
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XTT Cell Proliferation Assay Kit
Item number: Cay10010200-480
Defining the mechanisms responsible for alterations in cell cycle progression is crucial to understanding many human diseases, most notably cancer. Cell proliferation assays have been widely used to assess cell cycle regulatory factors such as growth factors, cytokines, mitogens, and drugs. Cayman's XTT cell...
| Application: | Cell based assays |
From 81.00€
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SRT 1720 (hydrochloride)
Item number: Cay10011020-1
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
| Keywords: | CAY10559, SIRT 1933, N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide, hydrochloride |
| Application: | SIRT1 activator |
| CAS | 1001645-58-4 |
| MW: | 469.6 D |
From 53.00€
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FABP2 Blocking Peptide
Item number: Cay10010020-1
To be used in conjunction with Cayman's FABP2 polyclonal antibody (Catalog No. 10010019) to block protein-antibody complex formation during immunochemical analysis of FABP2.Synonyms: Fatty Acid Binding Protein 2, I-FABP, Intestinal-Fatty Acid Binding Protein 2. Amino Acids: human FABP2 amino acids 33-40....
| Keywords: | Fatty Acid Binding Protein 2, I-FABP, Intestinal-Fatty Acid Binding Protein 2 |
| Application: | WB |
177.00€
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BMS309403
Item number: Cay10010206-10
Fatty acid binding protein 4 (FABP4) is a lipid transport protein that is also known as adipocyte FABP and aP2. In addition to adipocytes, it is also abundant in macrophages, along with FABP5, the epidermal FABP. BMS309403 is a cell-permeable, potent inhibitor of FABP4 that targets the fatty acid-binding pocket (Ki...
| Keywords: | A-FABP Inhibitor, Adipocyte FABP Inhibitor, ALBP Inhibitor, aP2 Inhibitor, FABP4 Inhibitor, Fatty Acid Binding Protein 4... |
| Application: | Cell-permeable, potent FABP4 inhibitor |
| CAS | 300657-03-8 |
| MW: | 474.6 D |
From 60.00€
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AICAR
Item number: Cay10010241-100
AICAR is an activator of AMP-activated protein kinase (AMPK). It increases AMPK kinase activity in isolated hepatocytes (EC50 = ~500 µM) and reduces HMG-CoA reductase activity and fatty acid and sterol synthesis in these cells. AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of control cells and...
| Keywords: | Acadesine, AICA-Riboside, NSC 105823, 5-amino-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide |
| Application: | AMPK activator |
| CAS | 2627-69-2 |
| MW: | 258.2 D |
From 64.00€
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Palmitate (calcium salt)
Item number: Cay10010279-500
Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Palmitic acid is a common 16-carbon saturated fat that...
| Keywords: | Calcium palmitate, hexadecanoic acid, calcium salt |
| Application: | Bioactive lipid assays |
| CAS | 542-42-7 |
| MW: | 550.9 D |
From 15.00€
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PAF C-18-d4
Item number: Cay10010229-100
PAF C-18-d4 contains four deuterium atoms at the 9, 9', 10, and 10' positions. It is intended for use as an internal standard for the quantification of PAF C-18 by GC- or LC-mass spectrometry. PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the...
| Keywords: | 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine-9,9,10,10-d4 |
| Application: | Standard |
| MW: | 555.7 D |
From 34.00€
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Lyso-PAF C-18 -d4
Item number: Cay10010228-500
Lyso-PAF C-18-d4 contains four deuterium atoms at the 9, 9', 10, and 10' positions. It is intended for use as an internal standard for the quantification of Lyso-PAF C-18 by GC- or LC-mass spectrometry. Lyso-PAF C-18 can be formed by either the action of PAF-AH on PAF C-18 or by the action of a CoA-independent...
| Keywords: | 1-O-octadecyl-sn-glyceryl-3-phosphorylcholine-9,9,10,10-d4 |
| Application: | Standard |
| MW: | 513.7 D |
From 163.00€
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Apigenin
Item number: Cay10010275-100
Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 µM apigenin decreases the...
| Keywords: | Chamomile, Flavone, NSC 83244, Versulin, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Application: | CK2 inhibitor |
| CAS | 520-36-5 |
| MW: | 270.2 D |
From 82.00€
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Palmitoyl 3-carbacyclic Phosphatidic Acid
Item number: Cay10010293-500
Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a 5-membered ring with the sn-3 phosphate. Carba-derivatives of cPA (ccPA) are modified at the sn-2 (2-ccPA) or sn-3 (3-ccPA) linkage, preventing the opening of cPA to produce LPA....
| Keywords: | 3-ccPA 16:0, (2-hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methyl ester-hexadecanoic acid |
| Application: | Autotaxin inhibitor |
| CAS | 476310-22-2 |
| MW: | 390.5 D |
From 102.00€
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Oleoyl 3-carbacyclic Phosphatidic Acid
Item number: Cay10010299-500
Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a 5-membered ring with the sn-3 phosphate. Carba-derivatives of cPA (ccPA) are modified at the sn-2 (2-ccPA) or sn-3 (3-ccPA) linkage, preventing the opening of cPA to produce...
| Keywords: | 3-ccPA 18:1, (9Z)-9-octadecenoic acid, (2-hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methyl ester |
| Application: | Cyclic LPA analog |
| CAS | 779333-58-3 |
| MW: | 416.5 D |
From 102.00€
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ML-9
Item number: Cay10010236-100
ML-9 was originally identified as a selective Ca2+-calmodulin-dependent myosin light chain kinase inhibitor. Concentrations from 10-100 µM are effective at inhibiting vascular smooth muscle tension and reducing intracellular Ca2+ concentrations. ML-9 also inhibits PKB/Akt activity with an IC50 range of 10-50 µM in...
| Keywords: | 1-[(5-chloro-1-naphthalenyl)sulfonyl]hexahydro-1H-1,4-diazepine, monohydrochloride |
| Application: | Ser/Thr kinase inhibitor |
| CAS | 105637-50-1 |
| MW: | 361.3 D |
From 77.00€
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