9 products were found matching "Cay10010081"!

Prostaglandin E2 (PGE2) is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. It acts as a mediator of pain and inflammation and promotes bone destruction. The increased synthesis of PGE2 during inflammation can be accounted for by increased expression...

Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Cay-20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. SC-57461A is a potent, orally active inhibitor of LTA4 hydrolase that blocks ionophore-stimulated LTB4 synthesis in...

Lutein is a dietary carotenoid that has been found in eggs and yellow-colored fruits and vegetables and has diverse biological activities. It reduces hyperglycemia-induced mitochondrial DNA damage and production of reactive oxygen species (ROS) and promotes mitochondrial biogenesis in ARPE-19 cells when used at a...

Synonyms: SIRT1 (human recombinant).

Inotilone is a cyclooxygenase (COX) inhibitor found in mushrooms of Phellinus and Inonotus sps. that inhibits COX-2 over COX-1 with IC50 values of 0.03 and 0.36 µM, respectively. It is a poor inhibitor of hydroxysteroid dehydrogenase and xanthine oxidase (IC50s = 50.4 and 9.1 µM, respectively). Inotilone...

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PF-750 is a potent, time-dependent, irreversible FAAH inhibitor with IC50 values of 0.6 and 0.016 µM when preincubated with recombinant human FAAH for 5 and 60 minutes,...

Synonyms: Phosphatidylcholine Enzyme Mixture. Formulation: A lyophilized powder. Origin: Plant/Armoracia rusticana.

Formulation: 100 µl of caspase-3/7 substrate N-Ac-DEVD-N'-MC-R110 in DMSO.

Formulation: 800 µl of 1,000 mg/dl glucose.