4 products were found matching "Cay10010043-%25"!
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Mevastatin
Item number: Cay10010340-25
Mevastatin is a competitive HMG-CoA reductase inhibitor (Ki = 0.1 µM). In vivo, mevastatin (50 mg/kg) inhibits cholesterogenesis in the liver and ileum of normolipidemic rats, as well as enhances suppression of cholesterogenesis in cholesterol-fed rats or rats administered cholestyramine. Mevastatin also suppresses...
| Keywords: | Compactin, CS 500, L-637,312, ML 236B, NSC 281245, Statin I,... |
| Application: | HMG-CoA reductase inhibitor |
| CAS | 73573-88-3 |
| MW: | 390.5 D |
From 43.00€
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1-Oleoyl-2-hydroxy-sn-glycero-3-PA
Item number: Cay10010093-25
1-Oleoyl-2-hydroxy-sn-glycero-3-PA (1-Oleoyl LPA) is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by...
| Keywords: | 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid |
| Application: | Bioactive lipid assays |
| CAS | 65528-98-5 |
| MW: | 436.5 D |
From 35.00€
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Pravastatin (sodium salt)
Item number: Cay10010343-25
Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the "statin" class of cholesterol-lowering drugs. Pravastatin is a HMG-CoA reductase inhibitor that is a ring hydroxylated metabolite of mevastatin. It is a competitive inhibitor...
| Keywords: | 1S,2S,6S,7S,8R,8aR-hexahydro-betaR,deltaR,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid,... |
| Application: | Potent HMG-CoA reductase inhibitor |
| CAS | 81131-70-6 |
| MW: | 446.5 D |
From 35.00€
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AG-825
Item number: Cay10010243-25
The HER2/Neu proto-oncogene is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases (RTK) which includes EGFR, HER2/Neu, HER3 and HER4. Overexpression of HER2/Neu occurs in 25-30% of human breast and ovarian cancer. AG-825 is a selective ATP-competitive inhibitor of the...
| Keywords: | Tyrphostin AG-825, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide |
| Application: | HER-2/neu inhibitor |
| CAS | 149092-50-2 |
| MW: | 397.5 D |
From 38.00€
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