4 products were found matching "Cay10009987"!
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(±)-EX-527
Item number: Cay10009798-5
EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7...
| Keywords: | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
| Application: | SIRT1 inhibitor |
| CAS | 49843-98-3 |
| MW: | 248.7 D |
From 43.00€
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Lipid-based Drug Delivery Tools
1,2-Didecanoyl PC
Item number: Cay10009879-50
Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC (DPC) is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of...
| Keywords: | 1,2-Didecanoyl Phosphatidylcholine, Didecanoyl Lecithin, 1,2-bis(O-decanoyl)-sn-glyceryl-3-phosphorylcholine |
| Application: | Bioactive lipid assays |
| CAS | 3436-44-0 |
| MW: | 565.7 D |
From 22.00€
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(±)5(6)-EET-d11
Item number: Cay10009984-10
(±)5(6)-EET-d11 is intended for use as an internal standard for the quantification of 5(6)-EET by GC- or LC-MS. 5(S),6(R)-EET and 5(R),6(S)-EET are formed via epoxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) by a variety of cytochrome P450 (CYP) isoforms, including CYP2B1, CYP2B2, CYP2C11,...
| Keywords: | (±)5,6-EET-d11, (±)5(6)-epoxy-8Z,11Z,14Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
| Application: | Standard |
| MW: | 331.5 D |
From 161.00€
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Dimethoxycurcumin
Item number: Cay10009986-10
Dimethoxycurcumin is a derivative of curcumin (Cay-81025) that has anti-inflammatory and antioxidant activities. It inhibits mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as secretion of IL-2, IL-4, IL-6, and IFN-gamma induced by concanavalin A (Cay-14951) in isolated human...
| Keywords: | Di-O-methylcurcumin, 1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione |
| Application: | Curcumin analog |
| CAS | 160096-59-3 |
| MW: | 396.4 D |
From 39.00€
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