- Search results for Cay10009928-%25
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6 products were found matching "Cay10009928-%25"!
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Item number: Cay10009998-25
(±)8(9)-DiHET-d11 is intended for use as an internal standard for the quantification of 8(9)-DiHET by GC- or LC-MS. 8(S),9(S)-DiHET and 8(R),9(R)-DiHET are vicinal diols formed via enzymatic hydration of 8(9)-EET by cytosolic or soluble epoxide hydrolases. 8(S),9(S)-DiHET is produced at a greater proportion than...
Keywords: | (±)8,9-DiHETrE-d11, (±)8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
Application: | Standard |
MW: | 349.6 D |
From 244.00€
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Item number: Cay10009984-25
(±)5(6)-EET-d11 is intended for use as an internal standard for the quantification of 5(6)-EET by GC- or LC-MS. 5(S),6(R)-EET and 5(R),6(S)-EET are formed via epoxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) by a variety of cytochrome P450 (CYP) isoforms, including CYP2B1, CYP2B2, CYP2C11,...
Keywords: | (±)5,6-EET-d11, (±)5(6)-epoxy-8Z,11Z,14Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
Application: | Standard |
MW: | 331.5 D |
From 161.00€
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Item number: Cay10009798-25
EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7...
Keywords: | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
Application: | SIRT1 inhibitor |
CAS | 49843-98-3 |
MW: | 248.7 D |
From 43.00€
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Item number: Cay10009598-25
6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 µM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6beta-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by...
Keywords: | 6,7-DHB, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octenyl]oxy]-7H-fuoro[3,2-g][1]benzopyran-7-one |
Application: | CYP3A4 inhibitor |
CAS | 145414-76-2 |
MW: | 372.4 D |
From 27.00€
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Lipid-based Drug Delivery Tools
Item number: Cay10009879-25
Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC (DPC) is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of...
Keywords: | 1,2-Didecanoyl Phosphatidylcholine, Didecanoyl Lecithin, 1,2-bis(O-decanoyl)-sn-glyceryl-3-phosphorylcholine |
Application: | Bioactive lipid assays |
CAS | 3436-44-0 |
MW: | 565.7 D |
From 22.00€
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Item number: Cay10009819-25
NF-kappaB p65 is a ubiquitously expressed transcription factor that is a subunit of the NF-kappaB complex and is encoded by the RELA gene in humans. It is composed of an N-terminal Rel homology domain, which mediates dimerization, nuclear localization, and DNA and protein interactions, and two C-terminal...
Keywords: | RELA, NFKB3, Transcription factor p65, Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor... |
Application: | WB |
530.00€
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