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(±)12(13)-EpOME-d4
(±)12(13)-EpOME-d4

Item number: Cay10009996-25

(±)12(13)-EpOME-d4 is intended for use as an internal standard for the quantification of 12(13)-EpOME by GC- or LC-MS. 12(13)-EpOME is an epoxide formed primarily via metabolism of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can...
Keywords: (±)-Vernolic Acid-d4, (±)12,13-EODE-d4, Isoleukotoxin-d4, (±)12(13)epoxy-9Z-octadecenoic-9,10,12,13-d4 acid
Application: Standard
MW: 300.5 D
From 149.00€ *
Review
(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol
(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

Item number: Cay10009962-25

2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. 2-AG is hydrolyzed by the enzyme monoacylglycerol lipase, terminating its biological activity, and metabolism by cyclooxygenase-2 and lipoxygenases has...
Keywords: (±)2-14,15-EG, (5Z,8Z,11Z)-13-(3-pentyl-2-oxiranyl)-5,8,11-tridecatrienoic acid, (±)2-hydroxy-1-(hydroxymethyl)ethyl ester
Application: Mitogen
CAS 848667-56-1
MW: 394.5 D
From 315.00€ *
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VO-OHpic (hydrate)
VO-OHpic (hydrate)

Item number: Cay10009965-25

VO-OHpic is a specific inhibitor of phosphatase and tensin homolog (PTEN, IC50 = 35 nM in vitro). Through this action, it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3) levels, phosphorylation of Akt, and glucose uptake in adipocytes. In mice, VO-OHpic (10 µg/kg, i.p.) decreases left ventricular...
Keywords: (OC-6-45)-aqua(3-hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)[3-(hydroxy-kappaO)-2-pyridinecarboxylato(2-)-kappaO2]oxo-v...
Application: PTEN inhibitor
CAS 476310-60-8
MW: 415.2 D
From 44.00€ *
Review