6 products were found matching "Cay10009852-%25"!

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Resolvin E1-d4
Resolvin E1-d4

Item number: Cay10009854-25

Resolvin E1-d4 (RvE1-d4) is intended for use as an internal standard for the quantification of RvE1 (Cay-10007848) by GC- or LC-MS. RvE1 is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) via an...
Keywords: RvE1-d4, 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic-6,7,14,15-d4 acid
Application: GC-MS, LC-MS, internal standard
MW: 354.5 D
From 226.00€ *
Review
PtdIns-(4,5)-P2 Binding Protein
PtdIns-(4,5)-P2 Binding Protein

Item number: Cay10009815-25

Pleckstrin homology (PH) domains all contain a seven-standard b-sandwich that allows binding to various species of phosphatidylinositol (PtdIns) phosphates. Most PH domains bind to PtdIns phosphates with weak affinity and low specificity. However, a small subclass binds specifically and with high-affinity for...
Keywords: Phosphatidylinositol-4,5-diphosphate, PI(4,5)-P2, PIP2, PLC-delta1-PH Domain
Application: WB
MW: 45,2 kD
From 163.00€ *
Review
(±)12(13)-DiHOME
(±)12(13)-DiHOME

Item number: Cay10009832-25

(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME (Cay-52450), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as isoleukotoxin. It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. 12(13)-DiHOME is toxic to Sf21 cells expressing sEH...
Keywords: Isoleukotoxin diol, 12,13-dihydroxy-9Z-octadecenoic acid
Application: Bioactive lipid assays
CAS 263399-35-5
MW: 314.5 D
From 43.00€ *
Review
MK-0524
MK-0524

Item number: Cay10009835-25

MK-0524 is a potent, selective prostaglandin D2 (PGD2) receptor DP1 antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively. It inhibits PGD2-induced accumulation of cAMP in both washed platelets and platelet-rich plasma with IC50 values of 0.09 and 4.0 nM, respectively. In a...
Keywords: Laropiprant, (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid
Application: DP1 receptor antagonist
CAS 571170-77-9
MW: 435.9 D
From 77.00€ *
Review
Valinomycin
Valinomycin

Item number: Cay10009152-5

Valinomycin is a cyclododecadepsipeptide potassium-selective ionophore antibiotic that is isolated from various strains of Streptomyces. The hydrophilic interior is the right size to accommodate the potassium ion, but not other ions, while the hydrophobic exterior allows the complex to pass through the lipid...
Keywords: NSC 122023,...
Application: Antibiotic
CAS 2001-95-8
MW: 1111.3 D
From 34.00€ *
Review
U-18666A
U-18666A

Item number: Cay10009085-25

Impaired trafficking of cholesterol to or from the endoplasmic reticulum (ER) has been implicated in many disease states including Neimann-Pick disease type C (NPC), Alzheimers disease and atherosclerosis. U-18666A is a cell permeable drug that inhibits cholesterol trafficking. It inhibits cholesterol transport from...
Keywords: 3beta-[2-(diethylamino)ethoxy]-androst-5-en-17-one, monohydrochloride
Application: Cholesterol trafficking studies
CAS 3039-71-2
MW: 424.1 D
From 65.00€ *
Review