- Search results for Cay10009851
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6 products were found matching "Cay10009851"!
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Item number: Cay10009851-100
Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphatase cycle, as well as with Ins(1,4,5,6)P4 in a...
Keywords: | 1,3,4,5,6-IP5 (sodium salt), Ins(1,3,4,5,6)P5, D-myo-inositol-1,3,4,5,6-penta(hydrogen phosphate), decaammonium salt |
Application: | Bioactive lipid assays |
MW: | 750.4 D |
From 84.00€
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Item number: Cay10009857-1
JTE-907 is a cannabinoid 2 (CB2) receptor inverse agonist. It is selective for CB2 over CB1 receptors (Kis = 35.9 and 2,370 nM, respectively, for the human receptors). JTE-907 increases forskolin-induced cAMP production in CHO cells expressing human or mouse CB2 receptors in a concentration-dependent manner. It...
Keywords: | N-(1,3-benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-quinolinecarboxamide |
Application: | Selective CB2 receptor antagonist / inverse agonist |
CAS | 282089-49-0 |
MW: | 438.5 D |
From 84.00€
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Item number: Cay10009835-1
MK-0524 is a potent, selective prostaglandin D2 (PGD2) receptor DP1 antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively. It inhibits PGD2-induced accumulation of cAMP in both washed platelets and platelet-rich plasma with IC50 values of 0.09 and 4.0 nM, respectively. In a...
Keywords: | Laropiprant, (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid |
Application: | DP1 receptor antagonist |
CAS | 571170-77-9 |
MW: | 435.9 D |
From 77.00€
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Item number: Cay10009875-1
Prostaglandin F2alpha (PGF2alpha), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 16-phenoxy PGF2alpha is a metabolically stable analog of PGF2alpha. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2alpha. Ethyl...
Keywords: | 16-phenoxy PGF2alpha ethyl amide, N-ethyl-9alpha,11alpha,15S-trihydroxy-16-phenoxy-prosta-5Z,13E-dien-1-amide |
Application: | PGF2alpha analog |
CAS | 951319-59-8 |
MW: | 417.5 D |
From 123.00€
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Item number: Cay10004985-1
Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-1 is a nutlin-3 analog which contains chlorine substituents at the 3 and 4 positions on two of the phenyl rings rather than a single 4-chloro as seen in nutlin-3. At high...
Keywords: | 4-[4,5-bis(3,4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carboxyl]-piperazin-2-one |
Application: | Nutlin-3 analog |
CAS | 1207480-88-3 |
MW: | 650.4 D |
From 85.00€
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Item number: Cay10009785-1
Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 phosphorylates dynamin at Ser774 and Ser778. Phosphorylation of these sites on dynamin is thought to play a key role in synaptic vesicle trafficking.Immunogen:...
Keywords: | Anti-phospho-Dnm, Anti-phospho-Dnm1, Anti-phospho-D100, EC=3.6.5.5, Anti-phospho-B-dynamin, Anti-phospho-Dynamin-1,... |
Application: | WB |
Host: | Sheep |
Species reactivity: | rat |
564.00€
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