2 products were found matching "Cay10009835-%25"!

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MK-0524
MK-0524

Item number: Cay10009835-25

MK-0524 is a potent, selective prostaglandin D2 (PGD2) receptor DP1 antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively. It inhibits PGD2-induced accumulation of cAMP in both washed platelets and platelet-rich plasma with IC50 values of 0.09 and 4.0 nM, respectively. In a...
Keywords: Laropiprant, (3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-1,2,3,4-tetrahydro-5-(methylsulfonyl)-cyclopent[b]indole-3-acetic acid
Application: DP1 receptor antagonist
CAS 571170-77-9
MW: 435.9 D
From 77.00€ *
Review
(±)12(13)-DiHOME
(±)12(13)-DiHOME

Item number: Cay10009832-25

(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME (Cay-52450), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as isoleukotoxin. It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. 12(13)-DiHOME is toxic to Sf21 cells expressing sEH...
Keywords: Isoleukotoxin diol, 12,13-dihydroxy-9Z-octadecenoic acid
Application: Bioactive lipid assays
CAS 263399-35-5
MW: 314.5 D
From 43.00€ *
Review