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Item number: Cay10009796-5

CAY10602 is an activator of sirtuin 1 (SIRT1). It inhibits LPS-induced TNF-alpha release in THP-1 cells when used at concentrations of 20 and 60 µM. CAY10602 (5 µM) decreases the expression of GPX4, SLC7A11, and SLC3A2, as well as increases the levels of iron and malondialdehyde (MDA), in A549 lung and MDA-MB-231...

Keywords:	1-(4-fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
Application:	SIRT1 activator
CAS	374922-43-7
MW:	418.4 D

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