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17(S)-HDHA
17(S)-HDHA

Item number: Cay10009799-25

17(S)-HDHA is a hydroxy fatty acid formed from docosahexaenoic acid (DHA, Cay-90310) by 15-lipoxygenase (15-LO) and is a precursor to 17(S)-resolvins. 17(S)-HDHA inhibits platelet 12-LO (IC50 = 0.4 µM). It inhibits TNF-alpha-induced expression of IL1B in a human glial cell line (IC50 = ~0.5 nM). 17(S)-HDHA (100 nM)...
Keywords: 17(S)-HDoHE, 17(S)-hydroxy Docosahexaenoic Acid, 17S-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid
Application: Bioactive lipid assays
CAS 92693-03-3
MW: 344.5 D
From 94.00€ *
Review
Ionomycin
Ionomycin

Item number: Cay10004974-5

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro...
Application: Ca Ionophore
CAS 56092-81-0
MW: 709 D
From 60.00€ *
Review