3 products were found matching "Cay10009747"!
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SLF
Item number: Cay10007974-5
FK-506 is a potent immunosuppressant that forms a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation. Synthetic ligand of FKBP (SLF) is a...
| Keywords: | Synthetic Ligand of FKBP, 1-(3,3-dimethyl-1,2-dioxopentyl)-(2S)-2-piperidinecarboxylic acid,... |
| Application: | FK-506 analog |
| CAS | 195513-96-3 |
| MW: | 524.7 D |
From 123.00€
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Lipid-based Drug Delivery Tools
D-erythro Lysosphingomyelin (d18:1)
Item number: Cay10007947-1
D-erythro Lysosphingomyelin is a bioactive sphingolipid. It is an agonist of sphingosine-1-phosphate receptor 1 (S1P1), S1P2, and S1P3 (EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors). D-erythro Lysosphingomyelin is also an agonist of the orphan receptor ovarian cancer G protein-coupled...
| Keywords: | D-erythro Lyso SM(18:1), D-erythro Sphingosine-1-Phosphocholine (d18:1), D-erythro-Sphingophosphorylcholine,... |
| Application: | Bioactive Lipid Assays |
| CAS | 1670-26-4 |
| MW: | 464.6 D |
From 121.00€
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PTEN (human recombinant)
Item number: Cay10009746-50
Phosphatase and tensin homology on chromosome 10 (PTEN) functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as AKT and phosphatidylinositol 3,4,5-trisphosphate (PIP3). PTEN interacts with many other proteins to regulate cell division and migration,...
| Keywords: | PTEN, MMAC1, Phosphatase and tensin homolog, Phosphatase and tensin homolog, Mutated in multiple advanced cancers 1,... |
| Application: | Enzyme activity |
| MW: | 50,8 kD |
611.00€
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