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1,2,3-Trieicosapentaenoyl Glycerol
1,2,3-Trieicosapentaenoyl Glycerol

Item number: Cay10009732-25

1,2,3-Trieicosapentaenoyl glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid (Cay-90110, Cay-21908), which is an omega-3 fatty acid. An EPA-TG emulsion, administered i.v., lowers leukotriene B4 production by 40% in polymorphonuclear leukocytes from rabbits and reduces platelet aggregation. It suppresses...
Keywords: EPA-TG, Glycerol Trieicosapentaenoate, TG(20:5/20:5/20:5),...
CAS 99660-94-3
MW: 945.4 D
From 43.00€ *
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Lipid-based Drug Delivery Tools
1,2-Dipalmitoyl-sn-glycero-3-PC
1,2-Dipalmitoyl-sn-glycero-3-PC

Item number: Cay10009473-25

1,2-Dipalmitoyl-sn-glycero-3-PC (1,2-DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications. It has been used in the formation of proteoliposomes for implantation of gamma-glutamyl transpeptidase into human...
Keywords: 1,2-Dipalmitoyl-sn-glycero-3-Phosphatidylcholine, 16:0/16:0-PC, DPPC, L-Dipalmitoyl Lecithin, PC(16:0/16:0),...
Application: Liposomal monolayer preparation
CAS 63-89-8
MW: 734.1 D
From 47.00€ *
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CAY10734
CAY10734

Item number: Cay10007833-25

CAY10734 is an agonist of sphingosine-1-phosphate receptor 1 (S1P1, IC50 = 0.6 nM). It selectively binds S1P1 over S1P2, S1P3, and S1P4 receptors (IC50s = >10,000, 12,000, and 70 nM, respectively) but does also bind S1P5 receptors (IC50 = 1 nM) in radioligand binding assays. CAY10734 reduces the number of peripheral...
Keywords: 1-[[4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]-3-azetidinecarboxylic acid
Application: S1P1 receptor agonist
CAS 635701-59-6
MW: 391.5 D
From 43.00€ *
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Purmorphamine
Purmorphamine

Item number: Cay10009634-25

Small molecules that promote osteoblast differentiation might be useful as therapeutic agents for bone diseases such as osteoporosis. Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts. The EC50 value for...
Keywords: 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
Application: Differentiation promotor
CAS 483367-10-8
MW: 520.6 D
From 39.00€ *
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Ionomycin
Ionomycin

Item number: Cay10004974-5

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro...
Application: Ca Ionophore
CAS 56092-81-0
MW: 709 D
From 60.00€ *
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