9 products were found matching "Cay10009661"!

Peroxisome proliferator-activated receptors (PPARs) play an essential role in regulating lipid and glucose metabolism. Oleoyl ethanolamide (OEA), a natural ligand for PPARalpha, has been shown to suppress food intake and reduce weight gain in rats when administered systemically at 10 mg/kg intraperitoneally....

Exendin-4 (48-86) amide is a 39-amino acid peptide fragment corresponding to residues 48-86 of exendin-4, a peptide produced in the salivary gland of the Gila monster, and an agonist of the glucagon-like peptide 1 receptor (GLP-1R, IC50 = 3.5 nM). Radiolabeled exendin-4 (48-86) amide localizes to the pancreas,...

Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that activates specific receptors located primarily in the gut and central nervous system. SB-242084 is an antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivity over other 5-HT, dopamine, or adrenergic receptors. In vivo, it...

Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin. More stable than curcumin in physiological media, DMC suppresses proliferation in cancer cells at 50-100 µM. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/beta-catenin pathway, and inhibits lipopolysaccharide...

CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution...

all-cis-1,2,3-Docosahexaenoyl glycerol is a polyunsaturated triacylglycerol that contains all-cis docosahexaenoic acid (DHA, Cay-90310) at the sn-1, sn-2, and sn-3 positions.Formal Name: (4Z,4'Z,4''Z,7Z,7'Z,7''Z,10Z,10'Z,10''Z,13Z,13'Z,13''Z,16Z,16'Z,16''Z,19Z,19'Z,19''Z)-4,7,10,13,16,19-docosahexaenoic acid,...

HDAC9 is a Class IIa HDAC which is homologous to the yeast HDAC1 and is larger in size than the other classes of HDACs. Class IIa HDACs contain a highly conserved C-terminal deacetylase catalytic domain (~420 amino acids) and N-terminal domain with no similarity to HDACs in other classes. Class II HDACs can shuttle...

Formulation: 100 ml of TBS buffer, pH 7.4, with 0.1% Polysorbate 20.

To be used in conjunction with Cayman's SREBP-2 polyclonal antibody (Catalog No. 10007663) to block protein-antibody complex formation during immunochemical analysis of SREBP-2 protein. · SREBPs, including SREBP-1a, SREBP-1c, and SREBP-2, constitute a family of basic helix-loop-helix (bHLH) transcription factors...