- Search results for Cay10009650
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6 products were found matching "Cay10009650"!
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Item number: Cay10009650-500
KIAA1363 is a 2-acetyl monoacylglyceryl ether (MAGE) hydrolase that is upregulated in aggressive cancers from various tissues. The enzyme catalyzes the hydrolysis of the 2-acetyl MAGE to MAGE and serves as a central enzyme in the PAF and LPA signaling network. AS 115 is a potent and selective inactivator of...
Keywords: | N-[2-[[(1S,2R)-2-(butoxymethyl)cyclohexyl]methoxy]ethyl]-2-fluorophenyl ester-carbamic acid |
Application: | KIAA1363 inactivator |
MW: | 381.5 D |
From 81.00€
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Item number: Cay10009996-50
(±)12(13)-EpOME-d4 is intended for use as an internal standard for the quantification of 12(13)-EpOME by GC- or LC-MS. 12(13)-EpOME is an epoxide formed primarily via metabolism of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can...
Keywords: | (±)-Vernolic Acid-d4, (±)12,13-EODE-d4, Isoleukotoxin-d4, (±)12(13)epoxy-9Z-octadecenoic-9,10,12,13-d4 acid |
Application: | Standard |
MW: | 300.5 D |
From 149.00€
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Item number: Cay11096-500
Exendin-4 (48-86) amide is a 39-amino acid peptide fragment corresponding to residues 48-86 of exendin-4, a peptide produced in the salivary gland of the Gila monster, and an agonist of the glucagon-like peptide 1 receptor (GLP-1R, IC50 = 3.5 nM). Radiolabeled exendin-4 (48-86) amide localizes to the pancreas,...
Keywords: | Exenatide Acetate |
Application: | GLP-1R agonist |
CAS | 914454-01-6 |
MW: | 4246.6 D |
From 135.00€
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Item number: Cay10009644-50
Sorafenib is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively). It is selective for these kinases over 12 other kinases, including ERK1,...
Keywords: | BAY 43-9006, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
Application: | Kinase inhibitor |
CAS | 284461-73-0 |
MW: | 464.8 D |
From 43.00€
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Item number: Cay10009661-50
Peroxisome proliferator-activated receptors (PPARs) play an essential role in regulating lipid and glucose metabolism. Oleoyl ethanolamide (OEA), a natural ligand for PPARalpha, has been shown to suppress food intake and reduce weight gain in rats when administered systemically at 10 mg/kg intraperitoneally....
Keywords: | N-octadecyl-N'-propyl-sulfamide |
Application: | PPARalpha activator |
CAS | 925891-74-3 |
MW: | 390.7 D |
From 102.00€
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Item number: Cay10009651-10
KIAA1363 is a recently characterized 2-acetyl monoacylglyceryl ether hydrolase that is critical to the survival and proliferation of many cancer cell lines. 2-thioacetyl MAGE is a colorimetric substrate for KIAA1363. It can readily be adapted to perform activity/inhibition studies of this new enzyme, using standard...
Keywords: | S-[2-(hexadecyloxy)-1-(hydroxymethyl)ethyl]ester, ethanethioic acid |
Application: | Bioactive lipid assays |
CAS | 112014-15-0 |
MW: | 374.6 D |
From 53.00€
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