9 products were found matching "Cay10009638"!

Immunogen: human TP receptor C-terminal amino acids 323-343 (LSTRPRSLSLQPQLTQRSGLQ). Formulation: (Request formulation change), 200 µg of peptide in 200 µl TBS, pH 7.4, containing 0.1% BSA and 0.02% sodium azide. Host: Rabbit. Applications: WB and ICC.

Formulation: 250 mM Tris-HCl, pH 8.0, containing 1.37 M NaCl, 27 mM KCl, and 10 mM MgCl2.

Small molecules that promote osteoblast differentiation might be useful as therapeutic agents for bone diseases such as osteoporosis. Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts. The EC50 value for...

FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. In vivo, FTY720...

This assay has been developed for researchers that do not have experience performing enzyme immunoassays (ELISAs). It can be used as a practice tool allowing you to become comfortable with running Cayman ELISAs. Practicing these assays can help to decrease errors when samples, time, and costs are at risk. This kit...

CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids, eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making...

FLLL32 is a cell-permeable analog of curcumin (Cay-81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM). It blocks signaling from IFN-alpha or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells. FLLL32 does not interfere with...

E-64 is a fungal metabolite originally isolated from Aspergillus japonicus that has diverse biological activities. It inhibits a variety of cysteine proteases, including cathepsins B, H, and L, as well as papain, ficin, and bromelain, but not the serine proteases plasmin, trypsin, and tissue kallikrein or the...

Prostaglandins have a short life in vivo because NAD+-dependent 15-hydroxy prostaglandin dehydrogenase (15-PGDH) catalyzes their oxidation to 15-keto metabolites with greatly reduced biological activity. Thiazolidinediones (TZDs) are a class of PPARgamma agonists that have potent 15-PGDH inhibitory activity....