- Search results for Cay10009625-%25
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11 products were found matching "Cay10009625-%25"!
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Item number: Cay10009996-25
(±)12(13)-EpOME-d4 is intended for use as an internal standard for the quantification of 12(13)-EpOME by GC- or LC-MS. 12(13)-EpOME is an epoxide formed primarily via metabolism of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can...
Keywords: | (±)-Vernolic Acid-d4, (±)12,13-EODE-d4, Isoleukotoxin-d4, (±)12(13)epoxy-9Z-octadecenoic-9,10,12,13-d4 acid |
Application: | Standard |
MW: | 300.5 D |
From 149.00€
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Item number: Cay10009645-25
Maslinic acid is found in a number of natural sources, most notably pomace olive oil (orujo). This pentacyclic triterpene has an antiproliferative effect against Caco-2 cancer cells (EC50 = 15 µM), HT-29 human colon cancer cells (EC50 = 74 µM), 1321N1 astrocytoma cells (IC50 = 25 µM), and human leukemia (CCRF-CEM...
Keywords: | 2alpha-Hydroxyoleanoic Acid, Crategolic Acid, 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid |
Application: | NO production inhibitor |
CAS | 4373-41-5 |
MW: | 472.7 D |
From 42.00€
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Item number: Cay10009651-25
KIAA1363 is a recently characterized 2-acetyl monoacylglyceryl ether hydrolase that is critical to the survival and proliferation of many cancer cell lines. 2-thioacetyl MAGE is a colorimetric substrate for KIAA1363. It can readily be adapted to perform activity/inhibition studies of this new enzyme, using standard...
Keywords: | S-[2-(hexadecyloxy)-1-(hydroxymethyl)ethyl]ester, ethanethioic acid |
Application: | Bioactive lipid assays |
CAS | 112014-15-0 |
MW: | 374.6 D |
From 53.00€
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Item number: Cay10009826-25
1,2,3-Triarachidonoyl glycerol is a polyunsaturated triacylglycerol with arachidonoyl (20:4) side-chains attached at the C-1, C-2, and C-3 positions that is useful in lipid research.Formal Name: (5Z,5'Z,5''Z,8Z,8'Z,8''Z,11Z,11'Z,11''Z,14Z,14'Z,14''Z)-5,8,11,14-eicosatetraenoic acid, 1,1',1''-(1,2,3-propanetriyl)...
Keywords: | Glycerol Triarachidonoyl, TG(20:4/20:4/20:4), Glycerol Trieicosatetraenoate, Optimar, Triarachidonin,... |
CAS | 23314-57-0 |
MW: | 951.5 D |
From 43.00€
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Item number: Cay10009286-25
Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. The EETs are released in response to acetylcholine, bradykinin, arachidonic acid, or cyclic stretch. (±)14(15)-EET-SI is the methyl sulfonamide analog of 14(15)-EET. This substitution...
Keywords: | 14(15)-EET-SI, 14(15)-EET-sulfonimide, 14,15-EpETrE-SI, N-(methylsulfonyl)-13-(3-pentyloxiranyl)-5Z,8Z,11Z-tridecatrienamide |
Application: | Bioactive lipid assays |
CAS | 218461-97-3 |
MW: | 397.6 D |
From 109.00€
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Item number: Cay10009634-25
Small molecules that promote osteoblast differentiation might be useful as therapeutic agents for bone diseases such as osteoporosis. Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts. The EC50 value for...
Keywords: | 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine |
Application: | Differentiation promotor |
CAS | 483367-10-8 |
MW: | 520.6 D |
From 39.00€
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Item number: Cay10009661-25
Peroxisome proliferator-activated receptors (PPARs) play an essential role in regulating lipid and glucose metabolism. Oleoyl ethanolamide (OEA), a natural ligand for PPARalpha, has been shown to suppress food intake and reduce weight gain in rats when administered systemically at 10 mg/kg intraperitoneally....
Keywords: | N-octadecyl-N'-propyl-sulfamide |
Application: | PPARalpha activator |
CAS | 925891-74-3 |
MW: | 390.7 D |
From 102.00€
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Item number: Cay10009644-25
Sorafenib is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively). It is selective for these kinases over 12 other kinases, including ERK1,...
Keywords: | BAY 43-9006, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
Application: | Kinase inhibitor |
CAS | 284461-73-0 |
MW: | 464.8 D |
From 43.00€
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Item number: Cay10009667-25
all-cis-1,2,3-Docosahexaenoyl glycerol is a polyunsaturated triacylglycerol that contains all-cis docosahexaenoic acid (DHA, Cay-90310) at the sn-1, sn-2, and sn-3 positions.Formal Name: (4Z,4'Z,4''Z,7Z,7'Z,7''Z,10Z,10'Z,10''Z,13Z,13'Z,13''Z,16Z,16'Z,16''Z,19Z,19'Z,19''Z)-4,7,10,13,16,19-docosahexaenoic acid,...
Keywords: | all-cis-1,2,3-Docosahexaenoyl-rac-glycerol, all-cis-Glycerol Tridocosahexaenoate, all-cis-Tridocosahexaenoic Acid,... |
CAS | 124596-98-1 |
MW: | 1023.5 D |
From 43.00€
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Item number: Cay10009366-25
Piceatannol is a stilbene that has been found in red wine and an active metabolite of trans-resveratrol (Cay-70675), a polyphenol with diverse biological activities. It is formed from trans-resveratrol by the cytochrome P450 (CYP) isoform CYP1B1. Piceatannol induces apoptosis in BJAB B cell lymphoma cells (EC50 = 25...
Keywords: | trans-3,3',4,5'-Tetrahydroxystilbene, trans-Picetannol, Astringenin, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-1,2-benzenediol |
Application: | Resveratrol analog, apoptosis inducer, antiproliferative, antiinflammatory agent, kinase inhibitor |
CAS | 10083-24-6 |
MW: | 244.2 D |
From 65.00€
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Item number: Cay10009816-25
(+)-Nutlin-3 is the enantiomer and less active form of the p53-Mdm2 protein-protein interaction inhibitor (-)-nutlin-3 (Cay-18585). It inhibits the interaction between p53 and Mdm2 150-fold less potently than (-)-nutlin-3 with an IC50 value of 13.6 µM. (+)-Nutlin-3 has been used as a negative control for the...
Keywords: | Nutlin 3b,... |
Application: | Control |
CAS | 675576-97-3 |
MW: | 581.5 D |
From 84.00€
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