- Search results for Cay10009597-%25
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5 products were found matching "Cay10009597-%25"!
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Item number: Cay10009598-25
6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 µM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6beta-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by...
Keywords: | 6,7-DHB, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octenyl]oxy]-7H-fuoro[3,2-g][1]benzopyran-7-one |
Application: | CYP3A4 inhibitor |
CAS | 145414-76-2 |
MW: | 372.4 D |
From 27.00€
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Item number: Cay10009557-25
The maintenance of embryonic stem cells in culture typically requires feeder cells and various exogenous factors found in serum. Murine embryonic stem (mES) cells can be maintained in the absence of feeder cells and serum but require the leukemia inhibitor factor (LIF) and bone morphogenic protein (BMP) to prevent...
Keywords: | Pluripotin,... |
Application: | RasGAP/ERK1 inhibitor |
CAS | 839707-37-8 |
MW: | 550.5 D |
From 77.00€
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Item number: Cay10009197-25
Flavopiridol is an orally bioavailable inhibitor of cyclin dependent kinases (IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively). It also inhibits TEFb, a complex composed of Cdk9 and cyclin T1, with a Ki value of 3 nM. Flavopiridol inhibits transcription of a CMV promoter in HeLa...
Keywords: | Alvocidib, HL 275, HMR 1275, L-868,275,... |
CAS | 131740-09-5 |
MW: | 438.3 D |
From 66.00€
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Item number: Cay10009797-25
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Keywords: | SIRT1 Activator 3, Sirtuin 1 Activator 3,... |
Application: | SIRT1 assays |
CAS | 839699-72-8 |
MW: | 367.5 D |
From 86.00€
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Item number: Cay10008597-25
Arachidonoyl ethanolamide (AEA, anandamide) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA. Metabolism...
Keywords: | (±)8,9-EET Ethanolamide, N-(2-hydroxyethyl)-(±)8(9)-epoxy-5Z,11Z,14Z-eicosatrienoic amide |
Application: | Bioactive lipid assays |
MW: | 363.5 D |
From 119.00€
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