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6,7-dihydroxy Bergamottin
6,7-dihydroxy Bergamottin

Item number: Cay10009598-25

6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 µM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6beta-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by...
Keywords: 6,7-DHB, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octenyl]oxy]-7H-fuoro[3,2-g][1]benzopyran-7-one
Application: CYP3A4 inhibitor
CAS 145414-76-2
MW: 372.4 D
From 27.00€ *
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2,3-dinor Thromboxane B2-d9
2,3-dinor Thromboxane B2-d9

Item number: Cay10009584-25

2,3-dinor Thromboxane B2-d9 (2,3-dinor TXB2-d9) is intended for use as an internal standard for the quantification of 2,3-dinor TXB2 (Cay-19050) by GC- or LC-MS. TXB2 is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 2,3-dinor...
Keywords: 2,3-dinor TXB2-d9,...
Application: Internal standard, 2,3-dinor TXB2 quantification
MW: 351.5 D
From 244.00€ *
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(±)12(13)-DiHOME-d4
(±)12(13)-DiHOME-d4

Item number: Cay10009994-25

(±)12(13)-DiHOME-d4 is intended for use as an internal standard for the quantification of 12(13)-DiHOME by GC- or LC-MS. 12(13)-DiHOME is the diol form of 12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin. It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in...
Keywords: Isoleukotoxin diol-d4, (±)12,13-dihydroxy-9Z-octadecenoic-9,10,12,13-d4 acid
Application: Bioactive lipid assays
MW: 318.5 D
From 125.00€ *
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PSN632408
PSN632408

Item number: Cay10008594-25

GPR119 (previously designated SNORF25) is an orphan G protein-coupled receptor expressed predominantly in the pancreas and gastrointestinal tract in humans and in the brain, pancreas, and gastrointestinal tract in rodents. It mediates a reduction in food intake and body weight gain in rats upon treatment with oleoyl...
Keywords: 4-[[3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]methoxy]-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester
Application: GPR119 receptor agonist
CAS 857652-30-3
MW: 360.4 D
From 38.00€ *
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