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PtdIns-(3,4,5)-P3-biotin (sodium salt)
PtdIns-(3,4,5)-P3-biotin (sodium salt)

Item number: Cay10009531-25

The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any...
Keywords: Phosphatidylinositol-3,4,5-triphosphate C-8-biotin, PIP3-biotin,...
Application: Affinity probe
CAS 1415684-80-8
MW: 1155.8 D
From 212.00€ *
Review
POV-PC
POV-PC

Item number: Cay10031-25

Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at...
Keywords: 2-(5-oxovaleryl) Phosphatidylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine
Application: Bioactive lipid assays
CAS 121324-31-0
MW: 593.7 D
From 126.00€ *
Review
Mps1-IN-2
Mps1-IN-2

Item number: Cay19401-25

Mps1-IN-2 is an ATP-competitive inhibitor of the checkpoint kinase Mps1 (IC50 = 145 nM). It is 1,000-fold selective for Mps1 over a panel of 352 kinases at 10 µM, but does inhibit Plk1 (Kd = 61 nM).Formal Name:...
Keywords: 9-cyclopentyl-2-[[2-ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,7,8,9-tetrahydro-5-methyl-6H-pyrimido[4,5-b][1,4]dia...
Application: MPS1 inhibitor
CAS 1228817-38-6
MW: 480.6 D
From 43.00€ *
Review