6 products were found matching "Cay10009350"!
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Aldehyde Reactive Probe (trifluoroacetate salt)
Item number: Cay10009350-10
DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA. ARP reacts with...
| Keywords: | ARP, O-(Biotinylcarbazoylmethyl) Hydroxylamine,... |
| Application: | Aldehyde Reactive Probe |
| CAS | 627090-10-2 |
| MW: | 445.4 D |
From 81.00€
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(±)9(10)-DiHOME-d4
Item number: Cay10009993-50
(±)9(10)-DiHOME-d4 is intended for use as an internal standard for the quantification of 9(10)-DiHOME by GC- or LC-MS. (±)9(10)-DiHOME is the diol form of (±)9(10)-EpOME (Cay-52400), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as leukotoxin. It is formed from...
| Keywords: | Leukotoxin diol-d4, (±)9,10-dihydroxy-12Z-octadecenoic-9,10,12,13-d4 acid |
| Application: | Standard |
| MW: | 318.5 D |
From 95.00€
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Piceatannol
Item number: Cay10009366-50
Piceatannol is a stilbene that has been found in red wine and an active metabolite of trans-resveratrol (Cay-70675), a polyphenol with diverse biological activities. It is formed from trans-resveratrol by the cytochrome P450 (CYP) isoform CYP1B1. Piceatannol induces apoptosis in BJAB B cell lymphoma cells (EC50 = 25...
| Keywords: | trans-3,3',4,5'-Tetrahydroxystilbene, trans-Picetannol, Astringenin, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-1,2-benzenediol |
| Application: | Resveratrol analog, apoptosis inducer, antiproliferative, antiinflammatory agent, kinase inhibitor |
| CAS | 10083-24-6 |
| MW: | 244.2 D |
From 65.00€
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SKF 96365 (hydrochloride)
Item number: Cay10009312-50
SKF 96365 inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels with an IC50 value of approximately 10 µM. It inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 µM. SKF 96365 can distinguish receptor-mediated release in...
| Keywords: | 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-1H-imidazole, monohydrochloride |
| Application: | Calcium influx inhibitor |
| CAS | 130495-35-1 |
| MW: | 402.9 D |
From 27.00€
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PAC-1
Item number: Cay10009317-50
Apoptosis can be induced when procaspase-3 is activated and converted to caspase-3. Procaspase-activating compound 1 (PAC-1) is a procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3. PAC-1's effectiveness was found to be directly proportional to the...
| Keywords: | Procaspase-activating Compound 1, 4-(phenylmethyl)-1-piperazineacetic acid,... |
| Application: | Procaspase-3 activator |
| CAS | 315183-21-2 |
| MW: | 392.5 D |
From 145.00€
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6-Aminonicotinamide
Item number: Cay10009315-250
6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase (Ki = 0.46 µM). Through this action, 6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells...
| Keywords: | 6-AN, NSC 21206, SR 4388, 6-amino-3-pyridinecarboxamide |
| Application: | 6-phosphogluconate dehydrogenase inhibitor |
| CAS | 329-89-5 |
| MW: | 137.1 D |
From 20.00€
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