5 products were found matching "Cay10009348-%25"!
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6(S)-Lipoxin A4
Item number: Cay10049-25
6(S)-Lipoxin A4 (6(S)-LXA4) is an isomer of the trihydroxy fatty acid LXA4 (Cay-90410). It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) through double lipoxygenase-catalyzed reactions initiated by either 5-lipoxygenase (5-LO) followed by 12- or 15-LO, with a leukotriene A4 (LTA4)...
| Keywords: | 5(S),6(S),15(S)-TriHETE, 5(S),6(S)-Lipoxin A4, 6(S)-LXA4, 6-epi-Lipoxin A4,... |
| Application: | Bioactive lipid studies |
| CAS | 94292-80-5 |
| MW: | 352.5 D |
From 368.00€
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Sphingosine Kinase 1 (human, recombinant)
Item number: Cay10348-25
Sphingosine kinase (SPHK) is an important enzyme in the sphingolipid metabolic pathway. SPHKs phosphorylate D-erythro-sphingosine to yield sphingosine-1-phosphate (S1P). To date two isoforms of SPHK, SPHK1 and SPHK2, have been identified & characterized from mammalian cells. Among them, SPHK1 has been implicated to...
| Keywords: | SK 1, SK 1, SPK 1, SPK 1, Sphingosine kinase 1, Sphingosine kinase 1, Acetyltransferase SPHK1, Acetyltransferase SPHK1 |
| Application: | Enzyme activity |
| MW: | 47,5 kD |
571.00€
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13,14-dihydro-15-keto Prostaglandin E2-d9
Item number: Cay19348-25
13,14-dihydro-15-keto-Prostaglandin E2-d9 (13,14-dihydro-15-keto PGE2-d9) is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGE2 (Cay-14650) by GC- or LC-MS. 13,14-dihydro-15-keto PGE2 is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is...
| Keywords: | 13,14-dihydro-15-keto PGE2-d9,... |
| Application: | GC-MS, LC-MS, internal standard |
| CAS | 2750534-81-5 |
| MW: | 361.5 D |
From 156.00€
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PF-4989216
Item number: Cay19308-25
PF-4989216 is an orally bioavailable broad-spectrum PI3K inhibitor (IC50s = 2, 142, 65, 1, and 110 nM for p110alpha, p110beta, p110gamma, p110delta, and VPS34, respectively). It inhibits the cell viability of small-cell lung cancer (SCLC) cells with a mutation in PIK3CA, blocking PI3K downstream signaling and...
| Keywords: | 4-(4-cyano-2-fluorophenyl)-2-(4-morpholinyl)-5-(1H-1,2,4-triazol-5-yl)-3-thiophenecarbonitrile |
| Application: | PI3K inhibitor |
| CAS | 1276553-09-3 |
| MW: | 380.4 D |
From 60.00€
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