- Search results for Cay10009315
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7 products were found matching "Cay10009315"!
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Item number: Cay10009315-100
6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase (Ki = 0.46 µM). Through this action, 6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells...
Keywords: | 6-AN, NSC 21206, SR 4388, 6-amino-3-pyridinecarboxamide |
Application: | 6-phosphogluconate dehydrogenase inhibitor |
CAS | 329-89-5 |
MW: | 137.1 D |
From 20.00€
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Item number: Cay10009931-5
24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that has important roles in cholesterol homeostasis. It is generated by the action of CYP46 on cholesterol in the brain and diffuses across the blood-brain barrier to the systemic circulation where it can modulate cell signaling, be used for further...
Keywords: | Cerebrosterol, cholest-5-ene-3beta,24S-diol |
Application: | LXR alpha / beta agonist |
CAS | 474-73-7 |
MW: | 402.7 D |
From 92.00€
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Item number: Cay10009312-5
SKF 96365 inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels with an IC50 value of approximately 10 µM. It inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 µM. SKF 96365 can distinguish receptor-mediated release in...
Keywords: | 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-1H-imidazole, monohydrochloride |
Application: | Calcium influx inhibitor |
CAS | 130495-35-1 |
MW: | 402.9 D |
From 27.00€
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Item number: Cay10009317-25
Apoptosis can be induced when procaspase-3 is activated and converted to caspase-3. Procaspase-activating compound 1 (PAC-1) is a procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3. PAC-1's effectiveness was found to be directly proportional to the...
Keywords: | Procaspase-activating Compound 1, 4-(phenylmethyl)-1-piperazineacetic acid,... |
Application: | Procaspase-3 activator |
CAS | 315183-21-2 |
MW: | 392.5 D |
From 145.00€
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Item number: Cay10007931-5
17-phenyl trinor 8-iso Prostaglandin E2 (17-phenyl trinor 8-iso PGE2) is the C-8 epimer of 17-phenyl trinor PGE2, a synthetic analog of PGE2. 17-phenyl trinor PGE2 is an EP1 and EP3 receptor agonist that causes contraction of the guinea pig ileum at a concentration of 11 µM. There are no published studies of the...
Keywords: | 9-oxo-11alpha,15S-dihydroxy-17-phenyl-18,19,20-trinor-(8beta)-prosta-5Z,13E-dien-1-oic acid |
Application: | EP1 receptor agonist, EP3 receptor agonist |
MW: | 386.5 D |
From 131.00€
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