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Sphingosine Kinase Inhibitor 2
Sphingosine Kinase Inhibitor 2

Item number: Cay10009222-25

Sphingosine kinase isoforms, SPHK 1 and SPHK 2 , catalyze the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 is an...
Keywords: SKI II, SPHK I2, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-phenol
Application: SPHK1 inhibitor
CAS 312636-16-1
MW: 302.8 D
From 54.00€ *
Review
PIK-93
PIK-93

Item number: Cay10009212-25

PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIbeta (PI4KIIIbeta, IC50 = 19 nM). It is selective for PI4KIIIbeta over PI4KIIIalpha and PI4KIIalpha (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110alpha, p110beta,...
Keywords: N-[5-[4-chloro-3-[[(2-hydroxyethyl)amino]sulfonyl]phenyl]-4-methyl-2-thiazolyl]-acetamide
Application: PI4K-beta inhibitor
CAS 593960-11-3
MW: 389.9 D
From 43.00€ *
Review