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6(S)-Lipoxin A4
6(S)-Lipoxin A4

Item number: Cay10049-25

6(S)-Lipoxin A4 (6(S)-LXA4) is an isomer of the trihydroxy fatty acid LXA4 (Cay-90410). It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) through double lipoxygenase-catalyzed reactions initiated by either 5-lipoxygenase (5-LO) followed by 12- or 15-LO, with a leukotriene A4 (LTA4)...
Keywords: 5(S),6(S),15(S)-TriHETE, 5(S),6(S)-Lipoxin A4, 6(S)-LXA4, 6-epi-Lipoxin A4,...
Application: Bioactive lipid studies
CAS 94292-80-5
MW: 352.5 D
From 368.00€ *
Review
GDC-0326
GDC-0326

Item number: Cay19241-5

GDC-0326 is an inhibitor of phosphatidylinositol 3-kinase alpha (PI3Kalpha, Ki = 0.2 nM) that is 133-, 20-, and 51-fold selective for PI3Kalpha over PI3Kbeta, PI3Kdelta, and PI3Kgamma, respectively. It inhibits proliferation of MCF7-neo/HER2 and PC3 cells (EC50s = 0.1 and 2.2 µM, respectively). In vivo, GDC-0326...
Keywords: (2S)-2-[[5,6-dihydro-2-[1-(1-methylethyl)-1H-1,2,4-triazol-5-yl]imidazo[1,2-d][1,4]benzoxazepin-9-yl]oxy]-propanamide
Application: PI3Kalpha inhibitor
CAS 1282514-88-8
MW: 382.4 D
From 43.00€ *
Review