- Search results for Cay10009232-%25
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7 products were found matching "Cay10009232-%25"!
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Item number: Cay10009222-25
Sphingosine kinase isoforms, SPHK 1 and SPHK 2 , catalyze the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 is an...
Keywords: | SKI II, SPHK I2, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-phenol |
Application: | SPHK1 inhibitor |
CAS | 312636-16-1 |
MW: | 302.8 D |
From 54.00€
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Item number: Cay10009212-25
PIK-93 is an inhibitor of phosphatidylinositol 4-kinase IIIbeta (PI4KIIIbeta, IC50 = 19 nM). It is selective for PI4KIIIbeta over PI4KIIIalpha and PI4KIIalpha (IC50s = 1,100 and >100,000 nM, respectively). However, it also inhibits the PI3K catalytic subunits (IC50s = 39, 590, 120, and 16 nM for p110alpha, p110beta,...
Keywords: | N-[5-[4-chloro-3-[[(2-hydroxyethyl)amino]sulfonyl]phenyl]-4-methyl-2-thiazolyl]-acetamide |
Application: | PI4K-beta inhibitor |
CAS | 593960-11-3 |
MW: | 389.9 D |
From 43.00€
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Item number: Cay10009023-25
(+)-WIN 55,212-2 (mesylate) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Ki values of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. In primary cultures of rat cerebral cortex neurons, (+)-WIN 55,212-2 (mesylate) (0.01-100 nM) increases extracellular glutamate...
Keywords: | [(3R)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone,... |
Application: | Aminoalkylindole CB receptor agonist |
CAS | 131543-23-2 |
MW: | 522.6 D |
From 62.00€
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Item number: Cay10007923-25
Epoxyeicosatrienoic acid (EpETrE, EET) metabolites of arachidonic acid such as 11(12)-EET and 14(15)-EET have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids...
Keywords: | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid |
Application: | sEH inhibitor |
CAS | 479413-68-8 |
MW: | 340.5 D |
From 64.00€
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Item number: Cay10009832-25
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME (Cay-52450), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as isoleukotoxin. It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. 12(13)-DiHOME is toxic to Sf21 cells expressing sEH...
Keywords: | Isoleukotoxin diol, 12,13-dihydroxy-9Z-octadecenoic acid |
Application: | Bioactive lipid assays |
CAS | 263399-35-5 |
MW: | 314.5 D |
From 43.00€
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Item number: Cay10009532-25
(±)8(9)-EET-d11 is intended for use as an internal standard for the quantification of (±)8(9)-EET (Cay-50351) by GC- or LC-MS. (±)8(9)-EET is a racemic mixture of the R/S enantiomeric forms biosynthesized from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). (±)8(9)-EET is a major cytochrome P450 (CYP)...
Keywords: | (±)8,9-EET-d11, (±)8,9-EpETrE-d11, (±)8(9)-epoxy-5Z,8Z,14Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
Application: | Standard |
MW: | 331.5 D |
From 161.00€
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Item number: Cay10009732-25
1,2,3-Trieicosapentaenoyl glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid (Cay-90110, Cay-21908), which is an omega-3 fatty acid. An EPA-TG emulsion, administered i.v., lowers leukotriene B4 production by 40% in polymorphonuclear leukocytes from rabbits and reduces platelet aggregation. It suppresses...
Keywords: | EPA-TG, Glycerol Trieicosapentaenoate, TG(20:5/20:5/20:5),... |
CAS | 99660-94-3 |
MW: | 945.4 D |
From 43.00€
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