- Search results for Cay10009115
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5 products were found matching "Cay10009115"!
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Item number: Cay10009115-100
p300/(CREB binding protein) associated factor (PCAF) belongs to the GCN5/PCAF family of nuclear histone acetyltransferases (HATs). Gcn5/PCAF proteins contain a ~160 residue HAT domain and a conserved bromodomain directly C-terminal to the HAT domain, which has been shown recently to be an acetyl-lysine targeting...
Keywords: | HAT, p300/(CREB binding protein) Associated Factor |
Application: | Enzyme activity |
MW: | 40 kD |
658.00€
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Item number: Cay10009911-5
Tangeretin is a polymethoxylated flavone isolated from peels of citrus fruits. It inhibits signaling in cancer cells, reducing ERK phosphorylation and growth of estradiol-stimulated T47D breast cancer cells (IC50 ~ 3 µM) and blocking p38 MAPK, JNK, and Akt activation in interleukin-1beta-stimulated human lung...
Keywords: | NSC 53909, NSC 618905, Ponkanetin, 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
Application: | Cancer studies |
CAS | 481-53-8 |
MW: | 372.4 D |
From 20.00€
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Item number: Cay10991-5
Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM). AFP...
Keywords: | 5Z-[3aR,3-difluorohexahydro-5R-hydroxy-4R-[3R-hydroxy-4S-methyl-1E-nonen-6aS-ynyl]-2Hcyclopenta[b]furan-2-ylidene]-pentano... |
Application: | IP receptor agonist |
CAS | 773825-80-2 |
MW: | 412.5 D |
From 369.00€
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Item number: Cay11091-5
Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability. The free acid of methylstat inhibits JMJD2A, JMJD2C, JMJD2E, PHF8, and JMJD3 with IC50 values of approximately 4.3, 3.4, 5.9, 10, and 43 µM, respectively, in an in vitro...
Keywords: | 4-[hydroxy[4-[[[4-[[[(1-naphthalenylamino)carbonyl]oxy]methyl]phenyl]methyl]amino]butyl]amino]-4-oxo-2E-butenoic acid,... |
Application: | JMJD2A / JMJD2C / JMJD2E / PHF8 / JMJD3 inhibitor prodrug |
MW: | 505.6 D |
From 73.00€
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Item number: Cay10009110-5
W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 (Cay-10009109). It only weakly binds to S1P1 (Ki = 4.6 µM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.Formal Name:...
Keywords: | [3S-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate) |
Application: | S1P1 Antagonist Control |
CAS | 909725-64-0 |
MW: | 456.4 D |
From 105.00€
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