- Search results for Cay10009110
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10 products were found matching "Cay10009110"!
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Item number: Cay10009110-500
W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 (Cay-10009109). It only weakly binds to S1P1 (Ki = 4.6 µM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.Formal Name:...
Keywords: | [3S-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate) |
Application: | S1P1 Antagonist Control |
CAS | 909725-64-0 |
MW: | 456.4 D |
From 105.00€
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Item number: Cay10009999-100
5(Z),11(Z),14(Z)-Eicosatrienoic acid is a polyunsaturated fatty acid found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods. A diet containing MPSO lowered high-density lipoprotein and ApoA1 levels in transgenic mice...
Keywords: | 5,11,14,20:3, Sciadonic Acid, 5Z,11Z,14Z-eicosatrienoic acid |
Application: | Bioactive lipid assays |
CAS | 7019-85-4 |
MW: | 306.5 D |
From 109.00€
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Item number: Cay11009-10
18-methyl Eicosanoic acid is a main component of the outer layer of the epicuticle of human hair and endows hydrophobicity to the outer hair surface. It is used as an additive to hair cosmetics due to its desirable conditioning effects.Formal Name: 18-methyl-eicosanoic acid. CAS Number: 36332-93-1. Synonyms:...
Keywords: | 18-MEA, Anteisoheneicosanoic Acid, 18-methyl-eicosanoic acid |
Application: | Lipid studies |
CAS | 36332-93-1 |
MW: | 326.6 D |
From 109.00€
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Item number: Cay10009134-10
EpETrE metabolites of arachidonic acid such as 11(12-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding DiHETrEs thereby diminishing their activity. Inhibitors...
Keywords: | 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid |
Application: | sEH inhibitor screening |
CAS | 1028430-42-3 |
MW: | 373.4 D |
From 46.00€
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Item number: Cay10009152-10
Valinomycin is a cyclododecadepsipeptide potassium-selective ionophore antibiotic that is isolated from various strains of Streptomyces. The hydrophilic interior is the right size to accommodate the potassium ion, but not other ions, while the hydrophobic exterior allows the complex to pass through the lipid...
Keywords: | NSC 122023,... |
Application: | Antibiotic |
CAS | 2001-95-8 |
MW: | 1111.3 D |
From 34.00€
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Item number: Cay10009197-10
Flavopiridol is an orally bioavailable inhibitor of cyclin dependent kinases (IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively). It also inhibits TEFb, a complex composed of Cdk9 and cyclin T1, with a Ki value of 3 nM. Flavopiridol inhibits transcription of a CMV promoter in HeLa...
Keywords: | Alvocidib, HL 275, HMR 1275, L-868,275,... |
CAS | 131740-09-5 |
MW: | 438.3 D |
From 66.00€
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Item number: CAY10009109-10
W146 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (Ki = 77 nM). It is selective for S1P1 over S1P2, S1P3, and S1P5 receptors (Kis = >10 µM for all). W146 prevents ligand-induced receptor internalization in CHO cells and inhibits the phosphorylation of ERK1 and Akt when used at a concentration of 10 µM....
Keywords: | [3R-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate) |
Application: | S1P1 receptor antagonist |
CAS | 909725-62-8 |
MW: | 456.4 D |
From 101.00€
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Item number: Cay10009137-10
beta-Gal-NONOate is a nitric oxide (NO) donor which releases NO following activation by beta-galactosidase. beta-Gal-NONOate is stable in aqueous solution at neutral and acidic pH for several hours, exhibits good water solubility, and is able to cross the cell membrane. Following enzymatic hydrolysis,...
Keywords: | 1-O-(1-pyrrolidinyl-ONN-azoxy)-beta-D-glucopyranose |
Application: | NO donor |
CAS | 357192-77-9 |
MW: | 293.3 D |
From 50.00€
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Item number: Cay10009162-10
The effects of prostaglandin E2 (PGE2) are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for...
Keywords: | 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-benzeneacetamide |
Application: | EP4 receptor antagonist |
CAS | 439288-66-1 |
MW: | 544.6 D |
From 80.00€
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Item number: Cay10009195-10
Cannabinoid agonists are typically highly lipophilic compounds that require solubilization with either a surfactant agent or adherence to a water miscible substance such as albumin, Tween 80, or Emulphor. O-2545 is a potent water-soluble agonist of central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors...
Keywords: | 6a,7,10,10a-tetrahydro-3-[5-(1H-imidazol-1-yl)-1,1-dimethylpentyl]-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol,... |
Application: | CB1 receptor agonist, CB2 receptor agonist |
CAS | 874745-43-4 |
MW: | 445 D |
From 126.00€
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