7 products were found matching "Cay10009044"!
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Sorafenib
Item number: Cay10009644-10
Sorafenib is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively). It is selective for these kinases over 12 other kinases, including ERK1,...
| Keywords: | BAY 43-9006, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Application: | Kinase inhibitor |
| CAS | 284461-73-0 |
| MW: | 464.8 D |
From 43.00€
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TrxR Inhibitor
Item number: Cay10009094-1
Formulation: A lyophilized powder.
| Application: | TrxR inhibitor |
20.00€
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Anti-Prion Protein (Clone BAR 221)
Item number: Cay10009034-1
Prion Protein (PrP) and namely its abnormal isoform, partially reistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease. [Bertin...
| Keywords: | PrP |
| Application: | EIA, FC, IHC, WB |
| Host: | Mouse |
| Species reactivity: | human, bovine, mouse, sheep |
744.00€
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PGPC
Item number: Cay10044-500
PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress. It is found as a component in mildly oxidized LDL (MM-LDL) and in products formed from the oxidation of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (Ox-PAPC). PGPC activates peroxisome proliferator-activated receptor...
| Keywords: | 1-Hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine, 1-Palmitoyl-2-glutaryl phosphatidylcholine,... |
| Application: | Oxidized phospholipid |
| CAS | 89947-79-5 |
| MW: | 609.7 D |
From 35.00€
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Glucoraphanin (potassium salt)
Item number: Cay10009445-10
Glucoraphanin is a natural glycoinsolate found in cruciferous vegetables, including broccoli. It is converted to the isothiocyanate sulforaphane by the enzyme myrosinase. Sulforaphane has powerful antioxidant, anti-inflammatory, and anti-carcinogenic effects. It acts by activating nuclear factor erythroid 2-related...
| Keywords: | 1-thio-1-[5-(methylsulfinyl)-N-(sulfooxy)pentanimidate]-beta-D-glucopyranose, potassium salt |
| Application: | Nrf2 activator precursor, Chemopreventive agent |
| MW: | 436.5 D |
From 48.00€
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Arachidonoyl-1-thio-Glycerol
Item number: Cay10007904-1
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor. It is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol found in rat brain. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to arachidonic...
| Keywords: | 1-S-Arachidonoyl-1-mercapto-2,3-propanediol, 5Z,8Z,11Z,14Z-eicosatetraenyl,1-thio glycerol |
| Application: | Bioactive lipid assays |
| CAS | 1309664-54-7 |
| MW: | 394.6 D |
From 39.00€
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6(S)-Lipoxin A4
Item number: Cay10049-100
6(S)-Lipoxin A4 (6(S)-LXA4) is an isomer of the trihydroxy fatty acid LXA4 (Cay-90410). It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) through double lipoxygenase-catalyzed reactions initiated by either 5-lipoxygenase (5-LO) followed by 12- or 15-LO, with a leukotriene A4 (LTA4)...
| Keywords: | 5(S),6(S),15(S)-TriHETE, 5(S),6(S)-Lipoxin A4, 6(S)-LXA4, 6-epi-Lipoxin A4,... |
| Application: | Bioactive lipid studies |
| CAS | 94292-80-5 |
| MW: | 352.5 D |
From 368.00€
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