3 products were found matching "Cay10008907-%25"!

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Item number: Cay10008908-25

GPR40 (free fatty acid receptor 1, FFAR1) is a G protein-coupled receptor (GPCR) that is activated by saturated and unsaturated long chain fatty acids. It is thought to play a role in the potentiation of insulin secretion by fatty acids in a glucose-sensitive manner. GW 1100 is a selective antagonist of...

Keywords:	4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-benzoic acid, ethyl ester
Application:	GPR40 antagonist
CAS	306974-70-9
MW:	520.6 D

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CAY10505

Item number: Cay10009078-25

Phosphoinositide 3-kinase gamma (PI3Kgamma), expressed primarily in hematopoietic cells, plays several important roles in immunity. CAY10505 is a potent inhibitor of PI3K, selectively inhibiting the gamma isoform (IC50 = 30 nM) better than the alpha, beta, and delta isoforms (IC50 = 0.94, 20, and 20 µM,...

Keywords:	5-[[5-(4-fluorophenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
Application:	PI3K inhibitor
CAS	328960-84-5
MW:	289.3 D

From 50.00€ *

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Sphingosine (d18:1)

Item number: Cay10007907-25

Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces...

Keywords:	(-)-Sphingosine, D-erythro-Sphingosine C-18, 2S-amino-4E-octadecene-1,3R-diol
Application:	Bioactive lipid assays
CAS	123-78-4
MW:	299.5 D

From 60.00€ *

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