2 products were found matching "Cay10008882"!

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Item number: Cay10008822-1

Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...

Keywords:	LDP-341, MG-341, MLN341, NSC 681239, PS-341,...
Application:	Proteasome subunit beta type-1/5 inhibitor
CAS	179324-69-7
MW:	384.2 D

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Anti-SMAD1/5/8/9

Item number: Cay10822-1

SMADs are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs:SMAD1, SMAD2, SMAD3, SMAD5, SMAD8, and SMAD9), common-mediator...

Application:	WB
Host:	Rabbit
Species reactivity:	human, mouse, rat

432.00€ *

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