7 products were found matching "Cay10008875"!
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13(S)-HODE methyl ester
Item number: Cay10008875-100
13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. The biological effects of 13(S)-HODE include inhibition of tumor cell adhesion to the endothelium at concentrations around 1 µM, and down regulation of...
| Keywords: | 13S-hydroxy-9Z,11E-octadecadienoic acid, methyl ester |
| Application: | Standard |
| CAS | 109837-85-6 |
| MW: | 310.5 D |
From 369.00€
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SR 1824
Item number: Cay11087-5
Peroxisome proliferator-activated receptor gamma (PPARgamma) is activated by the anti-diabetes drugs known as thiazolidinediones, including rosiglitazone (Cay-71740) and pioglitazone (Cay-71745). Phosphorylation of PPARgamma by cyclin-dependent kinase 5 (Cdk5) causes dysregulation of genes whose expression is...
| Keywords: | (S)-4'-((5-((1-(4-bromophenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid |
| Application: | Non-agonist PPARgamma ligand, Cdk5 inhibitor |
| CAS | 1338259-06-5 |
| MW: | 581.5 D |
From 84.00€
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(+)-2,5-epi Goniothalesdiol
Item number: Cay10008887-5
Goniothalesdiol, isolated from the bark of the Malaysian tree G. borneensis, is a tetrahydrofuran compound known to have significant cytotoxic effects against P388 murine leukemia cells and pesticidal activities. (+)-2,5-epi-Goniothalesdiol is a goniothalesdiol analog. Little is known of its biological...
| Keywords: | methyl 3-(3S,4S-dihydroxy-5S-phenyltetrahydrofuran-2R-yl)propanoate |
| Application: | Cytotoxic agent |
| CAS | 887927-59-5 |
| MW: | 266.3 D |
From 60.00€
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UNC669
Item number: Cay10875-10
UNC669 is an inhibitor of the MBT domain of L3MBTL1 with an IC50 value of 6 µM. It is 5- and 10-fold selective for L3MBTL1 over the related proteins L3MBTL3 and L3MBTL4.Formal Name: (5-bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]-methanone. CAS Number: 1314241-44-5. Molecular Formula: C15H20BrN3O. Formula...
| Keywords: | (5-bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]-methanone |
| Application: | L3MBTL1 antagonist |
| CAS | 1314241-44-5 |
| MW: | 338.2 D |
From 50.00€
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CAY10503
Item number: Cay10008872-5
CAY10503 is a proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase. CAY10503 inhibits the growth of HL60, multidrug resistant HL60R, and K562 cells with IC50 values of 7.0, 23, and 20 µM, respectively. Accumulation of HL60 cells in G0-G1 occurred within eight...
| Keywords: | 4-(4-hydroxyphenyl)phenyl-3,5-benzenediol |
| Application: | Proapoptotic reagent |
| CAS | 890854-82-7 |
| MW: | 278.3 D |
From 38.00€
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3-(N-Maleimidopropionyl)-biocytin
Item number: Cay10008879-5
3-(N-Maleimidopropionyl)-biocytin (MPB) is a versatile thiol-specific biotinylating reagent. It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6.5 and 7.5. This probe can be used in combination with the appropriate avidin- or...
| Keywords: | MPB,... |
| Application: | Biotinylation reagent |
| CAS | 102849-12-7 |
| MW: | 523.6 D |
From 22.00€
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Dimethylcurcumin
Item number: Cay10008187-5
Dimethylcurcumin is a selective enhancer of androgen receptor (AR) degradation. By disrupting the interaction between AR and its coregulators, dimethylcurcumin directs the degradation of AR and reduces signaling through this receptor both in cultured cells and in animals. In this way, dimethylcurcumin suppresses the...
| Keywords: | (1E,4Z)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-1,4,6E-heptatrien-3-one |
| Application: | Androgen receptor (AR) degradation enhancer |
| CAS | 52328-98-0 |
| MW: | 396.4 D |
From 60.00€
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