2 products were found matching "Cay10008872-%25"!

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Item number: Cay10008822-25

Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...

Keywords:	LDP-341, MG-341, MLN341, NSC 681239, PS-341,...
Application:	Proteasome subunit beta type-1/5 inhibitor
CAS	179324-69-7
MW:	384.2 D

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Dimethylcurcumin

Item number: Cay10008187-25

Dimethylcurcumin is a selective enhancer of androgen receptor (AR) degradation. By disrupting the interaction between AR and its coregulators, dimethylcurcumin directs the degradation of AR and reduces signaling through this receptor both in cultured cells and in animals. In this way, dimethylcurcumin suppresses the...

Keywords:	(1E,4Z)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-1,4,6E-heptatrien-3-one
Application:	Androgen receptor (AR) degradation enhancer
CAS	52328-98-0
MW:	396.4 D

From 60.00€ *

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