9 products were found matching "Cay10008841"!

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Propylpyrazole Triol
Propylpyrazole Triol

Item number: Cay10008841-1

Estrogen receptor alpha (ERalpha) and ERbeta are ligand-activated transcription factors that mediate the actions of estrogen. Activation of ERalpha, but not ERbeta, is required for the cardioprotective effects of estradiol. Propylpyrazole triol (PPT) is an ERalpha selective agonist with a 410-fold relative binding...
Keywords: PPT, 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)tris-phenol
Application: ERalpha agonist
CAS 263717-53-9
MW: 386.4 D
From 28.00€ *
Review
UNC0631
UNC0631

Item number: Cay11084-1

UNC0631 is a potent and selective inhibitor of G9a activity in vitro (IC50 = 4 nM) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC50 = 25 nM). It potently inhibits G9a/GLP activity in a variety of cancer cell lines as well as in the human fetal lung IMR-90 cell line.Formal Name:...
Keywords: N-[1-(cyclohexylmethyl)-4-piperidinyl]-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)...
Application: Potent, selective EHMT1 / EHMT2 inhibitor
CAS 1320288-19-4
MW: 635.9 D
From 50.00€ *
Review
D-myo-Inositol-1,5-diphosphate (sodium salt)
D-myo-Inositol-1,5-diphosphate (sodium salt)

Item number: Cay10008441-100

D-myo-Inositol-1,5-phosphate (Ins(1,5)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated...
Keywords: 1,5-IP2, Ins(1,5)-P2, D-myo-inositol-1,5-di(hydrogen phosphate), disodium salt
Application: Bioactive lipid assays
MW: 384.1 D
From 84.00€ *
Review
13,14-dihydro-15-keto Prostaglandin J2
13,14-dihydro-15-keto Prostaglandin J2

Item number: Cay10008840-1

Various biological properties exist for both prostaglandin J2 (PGJ2) and its metabolites such as inhibition of platelet aggregation, antitumor, and antiviral activity. 13,14-dihydro-15-keto PGJ2 is the dehydration product of 13,14-dihydro-15-keto PGD2 and is a presumed metabolite of PGJ2 via the 15-hydroxy PG...
Keywords: 11,15-dioxo-prosta-5Z,9-en-1-oic acid
Application: Bioactive lipid assays
MW: 334.5 D
From 163.00€ *
Review
CAY10573
CAY10573

Item number: Cay10008846-1

The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARalpha, gamma, and delta with IC50 values of 113, 50, and 223 nM, respectively. It...
Keywords: 5-[3-[(6-benzoyl-1-propyl-2-naphthalenyl)oxy]propoxy]-1H-indole-1-acetic acid
Application: PPAR agonist
CAS 853652-40-1
MW: 521.6 D
From 60.00€ *
Review
N-acetyl-2-carboxy Benzenesulfonamide
N-acetyl-2-carboxy Benzenesulfonamide

Item number: Cay10008284-1

N-acetyl-2-carboxy Benzenesulfonamide is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23. In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 µM and...
Keywords: 2-[(acetylamino)sulfonyl]-benzoic acid
Application: COX inhibitor
CAS 849067-18-1
MW: 243.2 D
From 24.00€ *
Review
Transcription Factor Goat Anti-Rabbit HRP Conjugate
Transcription Factor Goat Anti-Rabbit HRP Conjugate

Item number: Cay10006884-1

Formulation: 100 µl of goat anti-rabbit HRP-conjugated secondary antibody. Origin: Animal/Bovine, Animal/Goat.
Application: Kit component
68.00€ *
Review
Transcription Factor NF-kappaB Competitor dsDNA
Transcription Factor NF-kappaB Competitor dsDNA

Item number: Cay10007884-1

Application: Kit component
102.00€ *
Review
Transcription Factor Complete PPARgamma Positive Control
Transcription Factor Complete PPARgamma Positive Control

Item number: Cay10008894-1

Keywords: NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma
Application: Control
82.00€ *
Review