5 products were found matching "Cay10008840"!
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13,14-dihydro-15-keto Prostaglandin J2
Item number: Cay10008840-500
Various biological properties exist for both prostaglandin J2 (PGJ2) and its metabolites such as inhibition of platelet aggregation, antitumor, and antiviral activity. 13,14-dihydro-15-keto PGJ2 is the dehydration product of 13,14-dihydro-15-keto PGD2 and is a presumed metabolite of PGJ2 via the 15-hydroxy PG...
| Keywords: | 11,15-dioxo-prosta-5Z,9-en-1-oic acid |
| Application: | Bioactive lipid assays |
| MW: | 334.5 D |
From 163.00€
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PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt)
Item number: Cay10008400-100
The phosphatidylinositols (PtdIns) represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4)-P2 (1,2-dioctanoyl) is a synthetic analog of natural PtdIns featuring C8:0 fatty acids at the sn-1 and sn-2...
| Keywords: | DOPI-3,4-P2, Phosphatidylinositol-3,4-bisphosphate C-8, 1-(1,2R-dioctanoylphosphatidyl)inositol-3,4-bisphosphate,... |
| Application: | Bioactive lipid assays |
| MW: | 812.5 D |
From 85.00€
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Propylpyrazole Triol
Item number: Cay10008841-10
Estrogen receptor alpha (ERalpha) and ERbeta are ligand-activated transcription factors that mediate the actions of estrogen. Activation of ERalpha, but not ERbeta, is required for the cardioprotective effects of estradiol. Propylpyrazole triol (PPT) is an ERalpha selective agonist with a 410-fold relative binding...
| Keywords: | PPT, 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)tris-phenol |
| Application: | ERalpha agonist |
| CAS | 263717-53-9 |
| MW: | 386.4 D |
From 28.00€
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2,3-bis (4-Hydroxyphenyl) Propionitrile
Item number: Cay10008842-10
2,3-bis(4-Hydroxyphenyl)propionitrile (DPN) is an estrogen receptor beta (ERbeta) selective agonist. DPN exhibits a 70-fold higher relative binding affinity for ERbeta (18%) versus ERalpha (0.25%), about 80-fold higher transcriptional potency (EC50 = 0.85 nM versus 66 nM), and 170-fold higher relative potency (4.6%...
| Keywords: | DPN, 4-hydroxy-alpha-(4-hydroxyphenyl)-benzenepropanenitrile |
| Application: | ERbeta agonist |
| CAS | 1428-67-7 |
| MW: | 239.3 D |
From 53.00€
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CAY10573
Item number: Cay10008846-10
The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARalpha, gamma, and delta with IC50 values of 113, 50, and 223 nM, respectively. It...
| Keywords: | 5-[3-[(6-benzoyl-1-propyl-2-naphthalenyl)oxy]propoxy]-1H-indole-1-acetic acid |
| Application: | PPAR agonist |
| CAS | 853652-40-1 |
| MW: | 521.6 D |
From 60.00€
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