- Search results for Cay10008673
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13 products were found matching "Cay10008673"!
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Item number: Cay10008672-50
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) and COX-2 inhibitor (IC50 = 0.05 µM). It is selective for COX-2 over COX-1 (IC50 = 22.9 µM). Celecoxib induces apoptosis in BJAB and Jurkat cancer cells in a concentration-dependent manner. It reduces blood glucose levels in a rat model of diabetes induced...
Keywords: | SC-58635, YM-177, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
Application: | COX-2 inhibitor |
CAS | 169590-42-5 |
MW: | 381.4 D |
From 60.00€
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Item number: Cay10008671-10
Sildenafil is a potent inhibitor of phosphodiesterase 5 (PDE5) with IC50 values of 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively. It is selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 µM, respectively). Sildenafil reverses glucose-induced decreases...
Keywords: | 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one |
Application: | PDE5 inhibitor |
CAS | 139755-83-2 |
MW: | 474.6 D |
From 64.00€
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Item number: Cay10008613-1
Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a ligand-activated transcription factor involved in the regulation of lipid homeostasis. Activation of PPARalpha results in expression of a variety of genes, particularly those involved in fatty acid beta-oxidation, binding, and transport. GW 7647 is a...
Keywords: | 2-methyl-2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-propanoic acid |
Application: | PPARalpha agonist |
CAS | 265129-71-3 |
MW: | 502.8 D |
From 50.00€
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Item number: Cay10005673-5
HU-331 (Cay-10005673) is an analytical reference standard categorized as an oxidative degradation product of the phytocannabinoid cannabidiol (CBD, Cay-ISO60156, Cay-90080). This product is intended for research and forensic applications.Formal Name:...
Keywords: | Cannabidiol Hydroxy Quinone, Cannabidiolquinone, CBDHQ, CBDQ,... |
Application: | Analytical reference standard, oxidative degradation cannabidiol (CBD) product |
CAS | 137252-25-6 |
MW: | 328.5 D |
From 82.00€
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Item number: Cay10008643-100
Prostaglandin F2alpha-d9 (PGF2alpha-d9) is intended for use as an internal standard for the quantification of PGF2alpha (Cay-16010) by GC- or LC-ms. PGF2alpha is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also...
Keywords: | Dinoprost-d9, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid |
Application: | Standard |
MW: | 363.5 D |
From 65.00€
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Item number: Cay10007863-10
1,2-Dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for DAG kinases and multisubstrate lipid kinase.Formal Name: 9Z-octadecenoic acid,...
Keywords: | (±)-1,2-Diolein, rac-Glycerol 1,2-dioleate, 9Z-octadecenoic acid, 1,1'-[1-(hydroxymethyl)-1,2-ethanediyl] ester |
Application: | PKC activator, kinase substrate |
CAS | 2442-61-7 |
MW: | 621 D |
From 60.00€
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Item number: Cay10008663-5
LY2183240 is a potent, competitive inhibitor of anandamide uptake (IC50 = 270 pM, Ki = 540 pM) and hydrolysis. It increases anandamide levels in rat cerebellum (ED50 = 1.37 mg/kg) and displays dose-dependent efficacy (3-30 mg/kg) in several rodent models of persistent pain.Formal Name:...
Keywords: | 5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide |
Application: | Potent, competitive anandamide uptake inhibitor |
CAS | 874902-19-9 |
MW: | 307.4 D |
From 125.00€
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Item number: Cay10073-10
Abscisic acid (ABA) is a plant hormone with diverse roles in disease resistance, plant development, and response to stresses (water, salt, temperature, and pathogens). It is also produced by some plant pathogenic fungi. In addition to key roles in regulating stomatal closing, seed dormancy, and cell division, ABA...
Keywords: | (+)-ABA, Dormin, 5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-2Z,4E-pentadienoic acid |
Application: | Plant hormone |
CAS | 21293-29-8 |
MW: | 264.3 D |
From 28.00€
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Item number: Cay10008657-1
Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. Calcium-dependent cytosolic PLA2 (cPLA2alpha) is a 85 kDa enzyme that plays a key role in the arachidonic cascade and the inflammatory response associated with...
Keywords: | 1-[3-[4-(decyloxy)phenoxy]-2-oxopropyl]-1H-indole-3,5-dicarboxylic acid, 3-methyl ester |
Application: | cPLA2 inhibitor |
CAS | 888320-29-4 |
MW: | 523.6 D |
From 61.00€
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Item number: Cay10008647-5
11alpha-hydroxy Testosterone is a metabolite of testosterone, produced by the cytochrome P450 (CYP) isoform CYP3A. It can also be generated from testosterone by a mutant of CYP107A1 and from 11alpha-hydroxy progesterone by the fungus B. bassiana. The biological activity of this metabolite has not been...
Keywords: | 11alpha,17beta-dihydroxy-androst-4-en-3-one |
Application: | Bioactive lipid assays |
CAS | 3066-12-4 |
MW: | 304.4 D |
From 65.00€
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Item number: Cay10008617-5
Arachidonic acid leelamide is the arachidonic amide analog of leelamine. Leelamine has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with...
Keywords: | 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrene-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | Bioactive lipid assays |
MW: | 571.9 D |
From 72.00€
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Item number: Cay10009867-1
Formulation: 1 mg of Filipin III powder.
Application: | Kit component |
236.00€
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